Theoretical model for en face optical coherence tomography imaging and its application to volumetric differential contrast imaging

Tomita, Kiriko; Makita, Shuichi; Fukutake, Naoki; Morishita, Rion; El-Sadek, Ibrahim Abd; Mukherjee, Pradipta; Lichtenegger, Antonia; Tamaoki, Junya; Bian, Lixuan; Kobayashi, Makoto; Mori, Takahide; Matsusaka, Satoshi; Yasuno, Yoshiaki

doi:10.1364/boe.491510

Cited by 4 publications

References 29 publications

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Optimized Low‐Loss Ge₂Sb₂Te₅ Superlattice: Design, Fabrication and Application

Dong,

Wu,

Zhong

et al. 2024

Advanced Optical Materials

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Optical phase change materials (OPCMs) hold significant promise in photonic integrated circuits (PICs) due to their non‐volatile modulation capabilities through phase transition. Recently, integrating OPCMs with silicon devices has been leveraged to achieve multi‐level modulation in neural network computing. However, the conventional OPCM Ge2Sb2Te5 (GST), faces challenges in large‐scale PICs due to its large absorption. In this work, an optimized low‐loss GST superlattice is demonstrated, which significantly lowers crystalline attenuation coefficients from 2.69 to 0.539 dB µm−1, with negligible loss in amorphous state, while retaining excellent phase modulation capability. Additionally, 15 distinguishable extinction ratio states are achieved by manipulating irradiation energy for a hybrid Si microring resonator (MRR) embedded with GST superlattice. To further explore the potential application of GST superlattice in optical computing, an all‐optical tunable temporal differentiator is empirically demonstrated with a single hybrid MRR, achieving a broad dynamic differentiation order ranging from 0.7 to 1.3. The non‐volatile nature of OPCM facilitates low energy consumption and effectively optimizes chip density. The proposed structural design strategy to reduce the absorption loss is universal for any promising OPCMs feasible for large‐scale artificial intelligence‐driven PICs, including optical analog computing, optical switching and optical neural networks.

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Optimized Low‐Loss Ge₂Sb₂Te₅ Superlattice: Design, Fabrication and Application

Dong,

Wu,

Zhong

et al. 2024

Advanced Optical Materials

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Phase-Restoring Subpixel Image Registration: Enhancing Motion Detection Performance in Fourier-domain Optical Coherence Tomography

Tan

Pandiyan

et al. 2022

Preprint

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Phase-sensitive Fourier-domain optical coherence tomography (FD-OCT) enables label-free imaging of cellular movements in vivo with detection sensitivity down to the nanometer scale. Due to this high sensitivity, it is widely employed in various emerging functional imaging modalities such as optoretinography (ORG), optical coherence elastography (OCE), and optical coherence tomography angiography (OCTA). However, achieving shot-noise limited detection sensitivity remains a major challenge for in-vivo measurements where the sample is constantly affected by vascular pulsation, breathing, eye and head motion, and other involuntary movements. Here, we propose a phase-restoring subpixel motion correction (PRSMC) method for post-hoc image registration in FD-OCT. Based on a generalized FD-OCT model, this method enables translational shifts of OCT images by arbitrary displacements while accurately restoring physically meaningful phase components, both with subpixel precision. With the sample movements estimated from averaged Doppler shift or normalized cross-correlation, we reconstructed the OCT images by correcting the axial displacement in the spectrum (k) domain and the lateral displacement in the spatial frequency domain, respectively. We validated our method in simulations, phantom experiments, and in-vivo optoretinogram imaging, where the advantages over conventional approaches for both amplitude stability and phase accuracy were demonstrated. Our approach significantly reduces the motion-induced phase error (MIPE) when imaging moving samples, achieving systematic phase sensitivities close to the shot-noise regime.

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New formulation of OCT for analytical signal-to-speckle separation and volumetric differential contrast imaging

Tomita,

Makita,

Fukutake

et al. 2023

Optical Coherence Imaging Techniques and Imaging in Scattering Media V

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Theoretical model for en face optical coherence tomography imaging and its application to volumetric differential contrast imaging

Cited by 4 publications

References 29 publications

Optimized Low‐Loss Ge₂Sb₂Te₅ Superlattice: Design, Fabrication and Application

Optimized Low‐Loss Ge₂Sb₂Te₅ Superlattice: Design, Fabrication and Application

Phase-Restoring Subpixel Image Registration: Enhancing Motion Detection Performance in Fourier-domain Optical Coherence Tomography

New formulation of OCT for analytical signal-to-speckle separation and volumetric differential contrast imaging

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Theoretical model for en face optical coherence tomography imaging and its application to volumetric differential contrast imaging

Cited by 4 publications

References 29 publications

Optimized Low‐Loss Ge2Sb2Te5 Superlattice: Design, Fabrication and Application

Optimized Low‐Loss Ge2Sb2Te5 Superlattice: Design, Fabrication and Application

Phase-Restoring Subpixel Image Registration: Enhancing Motion Detection Performance in Fourier-domain Optical Coherence Tomography

New formulation of OCT for analytical signal-to-speckle separation and volumetric differential contrast imaging

Contact Info

Product

Resources

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Optimized Low‐Loss Ge₂Sb₂Te₅ Superlattice: Design, Fabrication and Application

Optimized Low‐Loss Ge₂Sb₂Te₅ Superlattice: Design, Fabrication and Application