Theoretical Studies of the Optical Properties of Hollow Spherical Metallic Nanoshells

Qian, Xiaohu; Bai, Jing Long

doi:10.1166/jctn.2013.3213

Cited by 2 publications

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“…The absorption spectrum of gold nanoshells depends on their thickness, as well as on the refraction index of both core and surrounding media [39]. Theoretical studies have shown that, for an air filled core of 10 nm size and a gold shell of 5 nm in water medium, the resonance peak is expected to occur at 538 nm, while, for a 10-nm shell, it should appear at 552 nm [40]. The increase of the core refraction index results in a red shift of the plasmon resonance peak [39].…”

Section: Resultsmentioning

confidence: 99%

Development of Multifunctional Liposomes Containing Magnetic/Plasmonic MnFe2O4/Au Core/Shell Nanoparticles

et al. 2018

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Multifunctional liposomes containing manganese ferrite/gold core/shell nanoparticles were developed. These magnetic/plasmonic nanoparticles were covered by a lipid bilayer or entrapped in liposomes, which form solid or aqueous magnetoliposomes as nanocarriers for simultaneous chemotherapy and phototherapy. The core/shell nanoparticles were characterized by UV/Visible absorption, X-Ray Diffraction (XRD), Transmission Electron Microscopy (TEM), and Superconducting Quantum Interference Device (SQUID). The magnetoliposomes were characterized by Dynamic Light Scattering (DLS) and TEM. Fluorescence-based techniques (FRET, steady-state emission, and anisotropy) investigated the incorporation of a potential anti-tumor drug (a thienopyridine derivative) in these nanosystems. The core/shell nanoparticles exhibit sizes of 25 ± 2 nm (from TEM), a plasmonic absorption band (λmax = 550 nm), and keep magnetic character. XRD measurements allowed for the estimation of 13.3 nm diameter for manganese ferrite core and 11.7 nm due to the gold shell. Aqueous magnetoliposomes, with hydrodynamic diameters of 152 ± 18 nm, interact with model membranes by fusion and are able to transport the anti-tumor compound in the lipid membrane, with a high encapsulation efficiency (EE (%) = 98.4 ± 0.8). Solid magnetoliposomes exhibit hydrodynamic diameters around 140 nm and also carry successfully the anticancer drug (with EE (%) = 91.2 ± 5.2), while also being promising as agents for phototherapy. The developed multifunctional liposomes can be promising as therapeutic agents for combined chemo/phototherapy.

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Section: Resultsmentioning

confidence: 99%

Development of Multifunctional Liposomes Containing Magnetic/Plasmonic MnFe2O4/Au Core/Shell Nanoparticles

et al. 2018

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“…Previous similar preparations of MnFe 2 O 4 nanoparticles resulted in an average size of ~25 nm [39]. From published theoretical studies [44], it is possible to conclude that the gold resonance peak is predicted to occur at 595.6 nm for a gold shell of 5 nm over an air core of 25 nm in a water medium, while if the gold shell is 10 nm, it is expected to occur at 552.2 nm. The increase in the core refraction index results in a red shift of the plasmon resonance peak [43].…”

Section: Synthesis Of Manganese Ferrite/gold Nanoparticlesmentioning

confidence: 93%

Magnetoliposomes Based on Magnetic/Plasmonic Nanoparticles Loaded with Tricyclic Lactones for Combined Cancer Therapy

Rio

Rodrigues

et al. 2021

Pharmaceutics

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Liposome-like nanoarchitectures containing manganese ferrite nanoparticles covered or decorated with gold were developed for application in dual cancer therapy, combining chemotherapy and photothermia. The magnetic/plasmonic nanoparticles were characterized using XRD, UV/Visible absorption, HR-TEM, and SQUID, exhibiting superparamagnetic behavior at room temperature. The average size of the gold-decorated nanoparticles was 26.7 nm for MnFe2O4 with 5–7 nm gold nanospheres. The average size of the core/shell nanoparticles was 28.8 nm for the magnetic core and around 4 nm for the gold shell. Two new potential antitumor fluorescent drugs, tricyclic lactones derivatives of thienopyridine, were loaded in these nanosystems with very high encapsulation efficiencies (higher than 98%). Assays in human tumor cell lines demonstrate that the nanocarriers do not release the antitumor compounds in the absence of irradiation. Moreover, the nanosystems do not cause any effect on the growth of primary (non-tumor) cells (with or without irradiation). The drug-loaded systems containing the core/shell magnetic/plasmonic nanoparticles efficiently inhibit the growth of tumor cells when irradiated with red light, making them suitable for a triggered release promoted by irradiation.

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Theoretical Studies of the Optical Properties of Hollow Spherical Metallic Nanoshells

Cited by 2 publications

References 0 publications

Development of Multifunctional Liposomes Containing Magnetic/Plasmonic MnFe2O4/Au Core/Shell Nanoparticles

Development of Multifunctional Liposomes Containing Magnetic/Plasmonic MnFe2O4/Au Core/Shell Nanoparticles

Magnetoliposomes Based on Magnetic/Plasmonic Nanoparticles Loaded with Tricyclic Lactones for Combined Cancer Therapy

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