Theoretical study of nematogenic behaviour of para-hexyl-p′-cyanobiphenyl

Chaturvedi, Shraddha; Chaturvedi, Navneet; Dwivedi, Manoj Kumar; Tiwari, Sugriva Nath

doi:10.1007/s12648-012-0212-1

Cited by 14 publications

(9 citation statements)

References 26 publications

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“…As we reported previously, 18 adding more than two equivalents of Fuc in the reaction system produced difucosylated LNDFH II Galβ3(Fucα4)GlcNAcβ3Galβ4(Fucα3)Glc ( 7), a hexasaccharide found in human milk at a concentration in the range 0.05 to 0.27 g L -1 . 44,[47][48] The preference of Hp3/4FT towards fucosylation of GlcNAc-containing disaccharide Galβ3GlcNAcβ motif to the Glc-containing disaccharide Galβ4Glc (Lac) motif in LNT is similar to what was observed previously 18 for its preference in the Galβ4GlcNAcβ motif to the Galβ4Glc (Lac) motif in lacto-N-neotetraose (LNnT), a type 2 glycan also found in HMOSs. Sialylfucosyllacto-N-tetraose (S-LNF II, 3) Neu5Acα3Galβ3(Fucα3)GlcNAcβ3Galβ4Glc was subsequently synthesized from LNFP II (2) using an OPME α2-3-sialylation system (OPME 4) containing Neisseria meningitidis CMP-sialic acid synthetase (NmCSS) 49 and Pasteurella multocida α2-3-sialyltransferase 1 M144D mutant (PmST1 M144D).…”

supporting

confidence: 78%

“…50 Lacto-N-difuco-hexaose I (LNDFH I, 4) Fucα2Galβ3(Fucα4)GlcNAcβ3Galβ4Glc, which has both α1-2and α1-4-linked fucose residues (Scheme 2), has been found in human milk at a concentration of 0.32-1.40 g L -1 . 44,47,51 It presents a terminal Lewis b structure that can bind to H. pylori and has been a candidate for developing potential therapeutics against H. pylori infection. 11,52 Attempts to fucosylate LNFP II (2) using an OPME fucosylation system (OPME 3b) containing Thermosynechococcus elongates α1-2-fucosyltransferase (Te2FT) 19 or Escherichia coli O126 α1-2-fucosyltransferase (EcWbgL) [53][54] were not successful, indicating that LNFP II (2) was not a suitable acceptor substrate for Te2FT or EcWbgL.…”

mentioning

confidence: 99%

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A Bacterial β1–3-Galactosyltransferase Enables Multigram-Scale Synthesis of Human Milk Lacto-N-tetraose (LNT) and Its Fucosides

McArthur

Chen

2019

ACS Catal.

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β1-3-Linked galactosides such as Galβ1-3GlcNAcβOR are common carbohydrate motifs found in human milk oligosaccharides (HMOSs), glycolipids, and glycoproteins. Efficient and scalable enzymatic syntheses of these structures have proven challenging due to the lack of access to a highly active β1-3-galactosyltransferase (β3GalT) in large amounts. Previously reported E. coli β3GalT (EcWbgO) has been identified as a limiting factor for producing a β1-3-galactoseterminated human milk oligosaccharide lacto-N-tetraose (LNT) by fermentation. Here we report the identification of an EcWbgO homolog from C. violaceum (Cvβ3GalT) which showed a high efficiency in catalyzing the formation of LNT from lacto-N-triose (LNT II). With the highly active Cvβ3GalT, multigram-scale (>10 gram) synthesis of LNT from lactose was achieved using a sequential one-pot multienzyme (OPME) glycosylation process. The access to Cvβ3GalT enabled enzymatic synthesis of several fucosylated HMOSs with or without further sialylation including LNFP II, S-LNF II, LNDFH I, LNFP V, and DiFuc-LNT. Among these, LNFP V and DiFuc-LNT would not be accessible by enzymatic synthesis if an active β3GalT were not available.

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supporting

confidence: 78%

mentioning

confidence: 99%

A Bacterial β1–3-Galactosyltransferase Enables Multigram-Scale Synthesis of Human Milk Lacto-N-tetraose (LNT) and Its Fucosides

McArthur

Chen

2019

ACS Catal.

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“…Several researchers, to suit various imaging situations, modified the Rayleigh criterion. To suit the case of object points of unequal intensities TOLANSKY [6], CHATURVEDI and SODHA [7] modified the Raleigh criterion. In the redefined Rayleigh criterion, the two objects points are said to be just resolved, if the contrast between the lower intensity peak LP BHATNAGAR, SIROHI and SHARMA [5] have employed the above modified Rayleigh criterion for case of unequally bright object points.…”

Section: The Rayleigh Criterionmentioning

confidence: 99%

“…The survey of the literature reveals that both the Rayleigh and Sparrow criteria were modified to suit various imaging situations, CHATURVEDI and SODHA [7], ASAKURA [4], JAISWAL and BHOGRA [12], BHATNAGAR, SIROHI and SHARMA [5], etc. CARSWELL and RICHARD [13] suggested a criterion for coherent system as an extension of Rayleigh criterion.…”

Section: Review Of Previous Work On Tprmentioning

confidence: 99%

“Trade-Off between Detection and Resolution of Two Point Objects Under Various Conditions of Imaging Situations: Part-I: Mathematical Formulation of the Problem”

Thirupathi¹

2013

IOSR-JM

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It is a well-experienced fact that whenever one tries to detect a weak object point in the vicinity of an intense point object, viz., a binary star-SIRUS and its companion weak satellite star, there is always loss of resolution of the optical system. In other words, one wants to improve the defectively of the system, there is always a loss of resolution capabilities of the system. Thus, there is a trade-off between Detection and Resolution of optical systems under various imaging situations. In this first paper of discussion of this trade-off, we have derived the Fourier analytical formulation of this problem. This formulation will be used to find out a compatible trade-off between Detection and Resolution in our further publications.

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“…Subsequently, to correlate the molecular structure with liquid crystal properties at the molecular level remains a subtle objective. To investigate the key role of molecular interactions in these compounds, several quantum mechanical studies have been led out by several workers [11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27] .…”

Section: Introductionmentioning

confidence: 99%

Theoretical and Experimental Study on the Effect of End Chain Length on Ultraviolet Absorption Behavior and Photostability of Alkoxy Benzoate Based Liquid Crystals

Defrawy¹,

Mohammady²,

Elghalban³

et al. 2017

Orient. J. Chem

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Liquid crystals homologous of 4-(4-chlorobenzoyloxy)phenyl 4-(n-alkoxy)benzoate (n CBPAB: n=8,14,16, where n is the number of carbon atoms in the alkoxy chain) were prepared and investigated for their liquid crystalline properties. The geometrical parameters and atomic charge distribution of the nCBPAB structures under investigation have been calculated using DFT level of calculation applying the B3LYP/6-31G(d) basis set. TD-DFT calculations have been used to predict the absorption spectra of the considered molecules. Furthermore, theoretically predicted molecular descriptors have been used to correlate with the phase stability of these molecules. In addition to that, the photo stability of these molecules has been investigated which provide valuable data for experimental applications.

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Theoretical study of nematogenic behaviour of para-hexyl-p′-cyanobiphenyl

Cited by 14 publications

References 26 publications

A Bacterial β1–3-Galactosyltransferase Enables Multigram-Scale Synthesis of Human Milk Lacto-N-tetraose (LNT) and Its Fucosides

A Bacterial β1–3-Galactosyltransferase Enables Multigram-Scale Synthesis of Human Milk Lacto-N-tetraose (LNT) and Its Fucosides

“Trade-Off between Detection and Resolution of Two Point Objects Under Various Conditions of Imaging Situations: Part-I: Mathematical Formulation of the Problem”

Theoretical and Experimental Study on the Effect of End Chain Length on Ultraviolet Absorption Behavior and Photostability of Alkoxy Benzoate Based Liquid Crystals

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