Energy saving is an important measure for the sustainable of opencast mining industry. However, the energy saving operation of crushing station is affected by vibration and collision in the process of open pit mining. This research aims to explore a novel strategy to reduce the high energy consumption of crushing station. Discrete element method (DEM), particle contact model and multiscale viscous particle model were used to analyse the operation process of crushing station. A multiparameter coupling coordinated speed regulation crushing strategy was proposed combined with the crusher model and simulation parameters. The practical application of this strategy in the crushing station of Shenbao energy open pit mine has been verified. The application results showed that compared with the manual operation control, the crushing efficiency of the crushing station is increased by 21.80%, the powder passing rate is reduced by 53.35%, and the operation energy saving of the crushing station is about 41.00%. The energy saving effect of multiparameter optimization is better than that of single parameter. This research provides a new theoretical basis for energy saving operation of crushing station in open pit mine.