-Diasporic immigrant literature as a political thought is not equal to "multiculturalism", which is not a political antidote for coordinating minorities and majorities. Taking Jeffrey Eugendies's Middlesex as an example, diasporic immigrant culture is full of paradoxes, among them there are "identity politics" and "politics of difference", which leads to the situation that the mainstream culture can't accommodate the immigrant culture because of the differences between cultures and different recognition of identity. Therefore, the best and possible way to solve this problem is cosmopolitanism.Index Terms -diasporic immigrant literature, culture identity, Middlesex Middlesex, which is the second novel of Jeffrey Kent Eugenides, is an informative and imaginative novel, including family secrets and many sensitive social issues, such as, race riots, war, immigrants and hermaphrodite, combining the romantic Greek mythology with the reality of American life ingeniously. This novel was set in the horizon of diaspora, adopting related theories on narrative discourse and culture identity, on the other hand, it depends on the Greek family of the novel in diaspora as the object to explore the efforts the diaspora make in pursuit of compromised identities in terms of ethnicity, religion, politics and religion.