Therapeutic abortion in Siriraj Hospital: A 10-year review

Chawanpaiboon, Saifon; Neungton, Chanon

doi:10.4236/ojog.2013.36088

Cited by 7 publications

(9 citation statements)

References 7 publications

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“…The well-trained neonatologists and excellent equipment result in the best care for newborns. 1 Our study found that a maternal risk factor for EONS was excessive weight gain during pregnancy, according to IOM recommendations (OR = 2.40, 95%CI = 1.16-4.94; p=0.016). According to Stotland NE, et al, who conducted a retrospective cohort study in singleton births, the rate of neonatal infection was higher when maternal weight gain was above IOM guidelines, when compared to the appropriate or low weight gain group (5.86%, 4.44% and 3.38% respectively).…”

Section: Discussionmentioning

confidence: 48%

“…At Siriraj Hospital, the incidence of preterm birth between 28 and 37 weeks of gestation is 9-13%. 1,2 Due to the immature development of several organs, these babies tend to have short-term or long-term morbidities in the respiratory system (respiratory distress syndrome, bronchopulmonary dysplasia, apnea of prematurity), gastrointestinal system (feeding intolerance, necrotizing enterocolitis, growth failure), immunological system (infection) and central nervous system (intraventricular hemorrhage, cerebral palsy, neurodevelopmental delay, hearing loss, retinopathy of prematurity). 3 One of the causes of preterm birth is preterm premature rupture of membranes (PPROM) in which the fetal membranes spontaneously rupture before completion of 37 weeks of gestation and onset of labor.…”

Section: Introductionmentioning

confidence: 99%

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Incidence and Risk Factors of Neonatal Sepsis in Preterm Premature Rupture of Membranes before 34 Weeks of Gestation

2022

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Objective: Early-onset neonatal sepsis (EONS) is a leading cause of newborn morbidity and mortality, particularly in preterm premature rupture of membranes (PPROM) before 34 weeks of gestation, in which expectant management was performed until reaching 34 weeks of gestation, evidence of maternal chorioamnionitis, or unfavorable fetal conditions. The interval between membrane rupture and delivery has a positive correlation with neonatal sepsis. The purpose of this study was to investigate the incidence and risk factors of EONS in PPROM.Materials and Methods: This was a retrospective cross-sectional study. The medical records of pregnant women who gave birth between 2005 and 2018 and their newborns were reviewed. The inclusion criterion was singleton pregnancies complicated by PPROM between 24 and 33+6 weeks of gestation. Multifetal pregnancies, fetal malformation, stillbirths, and records with incomplete data were excluded. PPROM was diagnosed by obstetricians while EONS was diagnosed by neonatologist.Results: The incidence of EONS in with PPROM was 24%. Risk factors included excessive maternal weight gain based on IOM (OR = 2.40, 95% CI = 1.16-4.94), extremely preterm at admission (before 28 weeks of gestation) (OR = 3.38, 95% CI 1.12-10.21) and very low birth weight (≤ 1,500 g) (OR 3.68, 95% CI = 1.86-7.30). Maternal hematologic laboratory results were not associated with neonatal sepsis.Conclusion: The incidence of EONS in PPROM was similar to data provided by other studies. Obstetricians and pediatricians should be cautious about neonatal sepsis, especially in cases of excessive maternal weight gain, extremely preterm admissions, and very low birth weight.

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Section: Discussionmentioning

confidence: 48%

Section: Introductionmentioning

confidence: 99%

Incidence and Risk Factors of Neonatal Sepsis in Preterm Premature Rupture of Membranes before 34 Weeks of Gestation

2022

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“…A recent review estimated that preterm birth affects approximately 11% of births worldwide [3]. In Thailand, the incidence of preterm deliveries has been reported to be 9%-13% with an upward trend [4,5].…”

Section: Introductionmentioning

confidence: 99%

Rate of Spontaneous Preterm Delivery Between Pregnant Women With and Without Gestational Diabetes

Boriboonhirunsarn¹,

Tanpong²

2023

Cureus

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The aim of this study is to compare the rate of spontaneous preterm delivery between gestational diabetes mellitus (GDM) and normal pregnancy. Pregnancy outcomes and associated risk factors for spontaneous preterm delivery were evaluated. MethodsA retrospective cohort study was conducted on 120 GDM and 480 normal pregnant women. All women received GDM screening with 50-g glucose challenge test and 100-g oral glucose tolerance test at the first visit and repeated at 24-28 weeks. Data were retrieved from medical records and included baseline and obstetric characteristics, preterm risks, GDM risks, and pregnancy outcomes. Spontaneous preterm birth was defined as delivery before 37 completed weeks of gestation that had been preceded by spontaneous labor. ResultsGDM women were more likely to be ≥30 years (p=0.032) and have previous GDM (p=0.013). Incidence of overall preterm delivery was significantly higher in GDM women (17.5% vs. 8.5%, p=0.004), as well as the incidence of spontaneous preterm delivery (15.8% vs. 7.1%, p=0.004). GDM women had less gestational weight gain (p<0.001) and were less likely to have excessive weight gain (p=0.002). GDM women were more likely to deliver large for gestational age (LGA) (p=0.02) and macrosomic infants (p=0.027). Neonatal hypoglycemia was significantly more common among GDM women (p=0.013). Multivariate analysis showed that previous preterm birth and GDM independently increased the risk of spontaneous preterm delivery

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“…[3] In Thailand, the incidence of preterm deliveries has been reported to be 9-13% with an upward trend. [4,5] Preterm delivery contributed to an increased risk of perinatal and neonatal mortality and morbidity.…”

Section: Introductionmentioning

confidence: 99%

Rate of spontaneous preterm delivery between gestational diabetes and normal pregnancy: A retrospective cohort study

Tanpong

Boriboonhirunsarn

2022

Preprint

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Background Preterm delivery has been reported to increase among women with gestational diabetes (GDM) but with conflicting results. Understand the relationship between the 2 conditions could help in better care of GDM and possibly minimize the risk of preterm delivery Therefore, the primary objective was to compare the rate of spontaneous preterm delivery between GDM and normal pregnancy. Moreover, pregnancy outcomes and associated risk factors for spontaneous preterm delivery were evaluated. Methods A retrospective cohort study was conducted in 120 GDM and 480 normal pregnant women. All women received GDM screening with 50-g GCT and 100-g OGTT at first visit and repeated at 24–28 weeks. Data was retrieved from medical records, including baseline and obstetric characteristics, preterm risks, GDM risks, and pregnancy outcomes. Spontaneous preterm birth was defined as delivery before 37 completed weeks of gestation that had been preceded by spontaneous labor. Results GDM women were more likely to be \(\ge\)30 years (p = 0.032), and have previous GDM (p = 0.013). Incidence of overall preterm delivery was significantly higher in GDM women (17.5% vs. 8.5%, p = 0.004) as well as incidence of spontaneous preterm delivery (15.8% vs. 7.1%, p = 0.004). GDM women had less gestational weight gain (p < 0.001) and were less likely to have excessive weight gain (p = 0.002). GDM women were more likely to deliver LGA (p = 0.02) and macrosomic infants (p = 0.027). Neonatal hypoglycemia was significantly more common among GDM (p = 0.013). Multivariate analysis showed that previous preterm birth and GDM independently increased risk of spontaneous preterm delivery (adjusted OR 2.56, CI 1.13–5.79, p 0.024 and adjusted OR 2.15, CI 1.2–3.84, p 0.010, respectively). Conclusion GDM and previous preterm birth significantly increased the risk of spontaneous preterm delivery. GDM also increased the risk of LGA, macrosomia, and neonatal hypoglycemia.

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Therapeutic abortion in Siriraj Hospital: A 10-year review

Cited by 7 publications

References 7 publications

Incidence and Risk Factors of Neonatal Sepsis in Preterm Premature Rupture of Membranes before 34 Weeks of Gestation

Incidence and Risk Factors of Neonatal Sepsis in Preterm Premature Rupture of Membranes before 34 Weeks of Gestation

Rate of Spontaneous Preterm Delivery Between Pregnant Women With and Without Gestational Diabetes

Rate of spontaneous preterm delivery between gestational diabetes and normal pregnancy: A retrospective cohort study

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