Therapeutic Approach to Chickenpox in Children and Adults - our Experience

Baljić, Rusmir; Mehanic, Snjezana; Imširović, Bilal; Ahmetspahic-Begic, Aida; Lukovac, Enra; Baljić, Izet; Hasimbegovic-Ibrahimovic, Selma; Gazibera, Belma; Gutosic, Maho

doi:10.5455/medarh.2012.66.s21-s23

Cited by 4 publications

(5 citation statements)

References 12 publications

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“…Acyclovir triphosphate is a competitive inhibitor of viral deoxyribonucleic acid synthesis and act as a chain terminator. 20,21 Strengths of the case report The study was conducted using face-to-face communication with the patient and was free from selection bias, response bias, and information bias. There is no feedback barrier among the investigator and respondent because the study was done through direct observational method.…”

Section: Discussionmentioning

confidence: 99%

Case Report: Account of chickenpox progression over 10 days

Bereda

2022

F1000Res

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Chickenpox is an extremely contagious disease; caused by the varicella-zoster virus primary infection. A 27-year-old adult Black African male health care worker presented with severe headache, intermittent weakness and inability to walk, intermittent nausea, fever, nocturnal polydipsia, shortness of breath, itching, pruritus (intensely pruritic erythematous macules), lesions with pus on the skin, sleep disturbances, and nightmares for two days. The most commonly occurring symptom of chickenpox is a vesicular rash that appears on the scalp, back and front of the neck, face and scapulae, and then disseminates distally to the limbs. In this case report, the patient face, neck and scapulae were the most infected areas of the body and the rest of the body except the legs, hands, genital areas and buttocks, were also highly infected. Acyclovir 800 mg orally, five times a day was given for ten days to cure chickenpox infection because acyclovir inhibits the replication of the varicella zoster virus, and has the ability to eradicate varicella zoster virus and relieve the symptoms more readily.

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Section: Discussionmentioning

confidence: 99%

Case Report: Account of chickenpox progression over 10 days

Bereda

2022

F1000Res

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“…Lotions and creams that comprise anti-histamines shouldn't use for chickenpox. 25 IV. Antiviral drug: Acyclovir has low oral bioavailability, only 15 to 20% of the dose reaches the plasma.…”

Section: Antihistaminic Drugsmentioning

confidence: 99%

“…The main goal of chickenpox infection management in children is to alleviate the symptoms such as skin infections, fever, itching and making the children comfortable. 24,25 There is several management of chickenpox; which discussed in turn below.…”

Section: Managementmentioning

confidence: 99%

“…Acyclovir inhibits the replication of the varicella zoster virus, and has the potential to eradicate varicella zoster virus and relieve symptoms more rapidly. 25,33 Acyclovir is phosphorylated by viral thymidine kinase to acyclovir monophosphate and then by cellular enzymes to acyclovir diphosphate and triphosphate. Acyclovir triphosphate is a competitive inhibitor of viral DNA secretion and act as a chain terminator.…”

Section: Antihistaminic Drugsmentioning

confidence: 99%

“…28IV. Isolation: If a rash develops, then continue isolation until all lesions are crusted or no new lesions appear within a 24 hours period and recommended as a children stay at home for five days 25. …”

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confidence: 99%

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Clinical manifestations, complications and management of chickenpox infection in pediatric

Bereda¹

2022

IPCB

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Chickenpox can be defined as a highly communicable viral infection caused by varicella zoster virus; most frequently influences pediatric in five to nine yrs old. The commonly occurred signs and symptoms of chickenpox are comprises vesicular rash appears on the scalp, face and trunk, and then disseminates distally to limbs (centrifugal distribution). The most common complications of chickenpox are bacterial soft-tissue infection, pneumonia, and encephalitis. Encephalitis is a most commonly occurred central nervous system complications expose the pediatric to other problems or death. The main goal chickenpox infection management in children is to alleviate the symptoms such as skin infections, fever, itching etc and making the children confortable. Adequate intravenous acyclovir administration is crucial for successful management of chickenpox, but it must be administered within twenty-four hrs. after the onset of the disease. Management of chickenpox with oral acyclovir given within twenty four hrs of onset of rash may be more effective.

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Viral Conditions

Cinteză¹

2021

Skin and the Heart

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Therapeutic Approach to Chickenpox in Children and Adults - our Experience

Cited by 4 publications

References 12 publications

Case Report: Account of chickenpox progression over 10 days

Case Report: Account of chickenpox progression over 10 days

Clinical manifestations, complications and management of chickenpox infection in pediatric

Viral Conditions

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