Therapeutic approaches in patients with bone metastasis due to endometrial carcinoma – A systematic review

Heidinger, Martin; Simonnet, Elisa; Koh, Li Mei; Tirri, Brigitte Frey; Vetter, Marcus

doi:10.1016/j.jbo.2023.100485

Cited by 1 publication

(1 citation statement)

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“…Their treatment primarily involves surgical procedures, complemented by adjunct therapies like radiation and chemotherapy, depending on tumour grade and stage. 2,3 While the survival rates, especially in the early stages, are relatively high, the aftermath of the treatment can have profound repercussions on the patient's life quality. 4,5 The pivotal role of sleep, fatigue, and psychological well-being in a patient's overall health and recovery cannot be understated.…”

Section: Introductionmentioning

confidence: 99%

Endometroid type endometrial cancer after surgery: unravelling the interplay of sleep, fatigue, and psychological well‐being

Sanci,

Görgülü,

Can

2024

Psychogeriatrics

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BackgroundEndometrioid carcinoma, originating in the endometrium glandular cells, is often detected early and treated by surgery. However, post‐treatment life quality remains poorly studied, explicitly focusing on sleep quality, fatigue, and depression.MethodsIn this cross‐sectional, observational study, 147 female patients with endometrioid‐type endometrial carcinoma were evaluated using standardised tools—Pittsburgh Sleep Quality Index (PSQI), Fatigue Assessment Scale (FAS), and Beck Depression Inventory (BDI). Patients were categorised based on sleep quality and depression levels. The study employed correlation and regression analyses to examine the relationships among these variables.ResultsNo correlations were found between sociodemographic or lifestyle variables and sleep quality, fatigue, or depression (P > 0.05). A strong correlation was identified between PSQI and FAS (r = 0.623; P < 0.001), PSQI and BDI (r = 0.291; P < 0.001), and FAS and BDI (r = 0.413; P < 0.001). Fatigue and tumour grade were potential predictors of poor sleep. Sleep quality and depression predicted fatigue, while only fatigue was a predictor for depression. Radiotherapy and external radiation rates were notably higher in the mild depression group.ConclusionsOur study suggests an imperative for integrated multi‐disciplinary approaches that focus on medical and psychological aspects of patient care to enhance long‐term well‐being and quality of life.

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