Therapeutic approaches to reducing atrophic acne scarring

Pavlidis, Athanasios; Katsambas, Andreas

doi:10.1016/j.clindermatol.2016.10.013

Cited by 10 publications

(6 citation statements)

References 16 publications

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“…Atrophic acne scarring on the face is often an unfortunate and permanent disfiguring sequela, and can have a serious negative effect on psychological well‐being and patients’ quality of life . There are a number of conventional approaches for the treatment of atrophic acne scarring, including surgical techniques (punch excisions, punch grafts and subcision), dermabrasion, chemical peels, ablative laser treatment, non‐ablative laser treatment, injection of dermal fillers, and autologous fat transfer . Although improvements in atrophic acne scars can be achieved with these techniques, they carry different risks of adverse side effects.…”

Section: Introductionmentioning

confidence: 99%

Treatment of atrophic acne scarring with fractional micro‐plasma radio‐frequency in Chinese patients: A prospective study

Lan

Tang

et al. 2018

Lasers Surg Med

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Section: Introductionmentioning

confidence: 99%

Treatment of atrophic acne scarring with fractional micro‐plasma radio‐frequency in Chinese patients: A prospective study

Lan

Tang

et al. 2018

Lasers Surg Med

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“…Acne scarring is caused by inadequate wound healing during active acne inflammation and may be associated with significant psychological distress …”

Section: Discussionmentioning

confidence: 99%

Efficacy and safety of plasma gel as a new modality in treatment of atrophic acne scars

Elfar

Hasby

2020

Int J Dermatology

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Background Postacne scarring is an unfortunate and frequent complication of acne, with varied morphological forms and associated significant psychological distress to patients.Aim of the work To evaluate the efficacy and safety of plasma gel injection alone and in combination with microneedling in treatment of atrophic postacne scars. Patients and methods Sixty patients with atrophic postacne scars were enrolled in this single blinded randomized controlled study. The patients were divided into three groups with 20 patients being treated with intradermal injection of plasma gel, 20 patients treated with dermaroller, and 20 patients subjected to combined plasma gel and dermaroller.Patients received four sessions at monthly intervals and were evaluated by clinical, histopathological, and immunohistochemical analysis. ResultsThere was statistically significant improvement in postacne scars after treatment in all studied groups with variable degrees; the combined technique showed the best clinical improvement in postacne scars. There was an increase in newly formed collagen and elastic fibers with more organized and condensed bundles after the end of treatment.Conclusion Plasma gel showed a remarkable improvement for most patients after one session, providing a quick and easy solution for acne scars. The combination of dermaroller and plasma gel potentiated its effect with more improvement in scars.The excluded subjects had active acne lesions, immunosuppression, bleeding or coagulation disorders, active infection at the site of injection, chronic disease (renal failure, hepatic insufficiency, cardiovascular disorders, uncontrolled diabetes mellitus, and thyroid disorders), keloid formation, unrealistic expectations, pregnancy, and lactation.The patients were simply randomized to each of the study groups using a computer-generated list. Allocation concealment was ensured by enclosing assignments in sequentially

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“…Atrophic acne scarring is a common and distressing condition found in many patients after severe acne. Numerous treatment approaches have been used for the treatment of acne scars (including surgical management, tissue augmentation, dermabrasion, chemical peels, ablative laser, nonablative laser), with varying degrees of success and incidence of side effects [13–15]. Among these modalities, ablative lasers have been thought to be the gold standard treatment for acne scars, but side effects such as PIH, prolonged erythema, and long downtime are common [13,16].…”

Section: Discussionmentioning

confidence: 99%

Comparison of Fractional Micro‐Plasma Radiofrequency and Fractional Microneedle Radiofrequency for the Treatment of Atrophic Acne Scars: A Pilot Randomized Split‐Face Clinical Study in China

et al. 2020

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Background and Objective Both fractional micro‐plasma radiofrequency (RF) and fractional microneedle RF are novel devices that can be applied for the treatment of atrophic acne scars, and they have both been proved to be effective. To compare the clinical effectiveness and adverse reactions of fractional micro‐plasma RF and fractional microneedle RF for the therapy of facial atrophic acne scars in a randomized split‐face study. Study Design/Materials and Methods Sixty patients with facial atrophic acne scars received three applications at 2‐month intervals in a randomized split‐face study using fractional micro‐plasma RF and fractional microneedle RF on different sides of the face. Three independent dermatologists evaluated the improvement in acne scars using the ECCA grading scale (Echelle d'Evaluation Clinique des Cicatrices d'Acné) by comparing the digital images and graded the improvement in the acne scars. Patients were asked to provide a self‐evaluation of satisfaction for efficacy and safety. Adverse effects were also recorded after each treatment. Results In total sixty patients completed the entire study. A significant improvement was observed in the appearance of acne scars, and the mean ECCA scores improved significantly after both modalities. The mean decrease in ECCA scores from the baseline was significantly more pronounced in fractional micro‐plasma RF as compared with fractional microneedle RF (41.33 ± 20.19 vs 32.17 ± 17.35; P < 0.05). The degree of clinical improvement was also significantly better for fractional micro‐plasma RF. Pain, erythema, and swelling were observed in all patients after both treatments. The pain was more intense during micro‐plasma RF treatment (P = 0.000), and the duration of pain and erythema were longer than with fractional microneedle RF (P = 0.000). Postinflammatory hyperpigmentation (PIH) was observed in one patient on the fractional micro‐plasma RF side while no PIH was observed on the fractional microneedle RF side. No infections or worsening of scarring was observed with either treatment. No subject was dissatisfied with the efficacy of either device. Rolling scars tended to respond better to fractional micro‐plasma RF treatment compared with fractional microneedle RF (P = 0.000). Conclusions Both fractional micro‐plasma RF and fractional microneedle RF are effective and safe methods for improving atrophic acne scars. Fractional micro‐plasma RF is significantly more effective for atrophic acne scars, especially for rolling scars. However, fractional microneedle RF has fewer side effects plus shorter downtime, and patients are more comfortable after the treatment. Lasers Surg. Med. © 2020 Wiley Periodicals LLC

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Therapeutic approaches to reducing atrophic acne scarring

Cited by 10 publications

References 16 publications

Treatment of atrophic acne scarring with fractional micro‐plasma radio‐frequency in Chinese patients: A prospective study

Treatment of atrophic acne scarring with fractional micro‐plasma radio‐frequency in Chinese patients: A prospective study

Efficacy and safety of plasma gel as a new modality in treatment of atrophic acne scars

Comparison of Fractional Micro‐Plasma Radiofrequency and Fractional Microneedle Radiofrequency for the Treatment of Atrophic Acne Scars: A Pilot Randomized Split‐Face Clinical Study in China

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