Therapeutic Challenges in the Management of Acute Myocardial Infarction in Polycythemia Vera

doi:10.4172/2155-9864.1000253

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2023

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“…Even though there is no current standard consensus on the management of acute MI in patients with polycythemia, percutaneous coronary intervention continues to be the gold standard. 17 These patients should be treated similarly to those without hematologic diseases because there appears to be a sizable outcome advantage with this approach. 18 Thus, this patient received percutaneous coronary intervention with a drug-eluting stent to a completely occluded LAD with successful flow recovery.…”

Section: Discussionmentioning

confidence: 99%

ST-Segment Elevation Myocardial Infarction and Bleeding Complications in JAK2-Negative Polycythemia

Duran Luciano,

Sabella-Jiménez

2023

Texas Heart Institute Journal

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Thrombotic and bleeding complications are major causes of morbidity and mortality in patients with polycythemia vera, who predominantly present with an alteration in the JAK2 gene. Because of their hypercoagulable state and risk of hemorrhage, patients with polycythemia vera who present with an acute myocardial infarction pose a challenge to physicians. This case report describes the presentation and treatment of a Hispanic patient with JAK2 V617F–negative primary polycythemia who developed cardiac arrest and ST-segment elevation myocardial infarction owing to complete occlusion of the left anterior descending artery as well as bleeding complications and postmyocardial pericarditis.

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Section: Discussionmentioning

confidence: 99%