Therapeutic drug monitoring of glycopeptide antimicrobials: An overview of liquid chromatography-tandem mass spectrometry methods

Cafaro, Alessia; Barco, Sebastiano; Pigliasco, Federica; Russo, Chiara; Mariani, Marcello; Mesini, Alessio; Saffioti, Carolina; Castagnola, Elio; Cangemi, Giuliana

doi:10.1016/j.jmsacl.2023.12.003

Journal of Mass Spectrometry and Advances in the Clinical Lab

2024

DOI: 10.1016/j.jmsacl.2023.12.003

|View full text |Cite

Therapeutic drug monitoring of glycopeptide antimicrobials: An overview of liquid chromatography-tandem mass spectrometry methods

Alessia Cafaro,

Sebastiano Barco,

Federica Pigliasco

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article4

Relationship

Self Cite0

Independent4

Authors

Journals

Cited by 4 publications

References 83 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Recent Trends in Therapeutic Drug Monitoring of Peptide Antibiotics

Kilianova,

Cizmarova,

Spaglova

et al. 2024

J of Separation Science

View full text Add to dashboard Cite

Antimicrobial peptides take a specific position in the field of antibiotics (ATBs), however, from a large number of available molecules only a few of them were approved and are used in clinics. These therapeutic modalities play a crucial role in the management of diseases caused by multidrug‐resistant bacterial pathogens and represent the last‐line therapy for bacterial infections. Therefore, there is a demand for a rationale use of such ATBs based on optimization of the dosing strategy to minimize the risk of resistance and ensure the sustainable efficacy of the drug in real clinical practice. Therapeutic drug monitoring, as a measurement of drug concentration in the body fluids or tissues, results in the optimization of the patient´s medication and therapy outcome. This strategy is beneficial and could result in tailored therapy for different types of infection and the prolongation of the use and efficacy of ATBs in hospitals. This review paper provides an actual overview of approved antimicrobial peptides used in clinical practice and covers current trends in their analysis by convenient and advanced methodologies used for their identification and/or quantitation in biological matrices for therapeutic drug monitoring purposes. Special emphasis is given to the methods with perspective clinical outcomes.

show abstract

Recent Trends in Therapeutic Drug Monitoring of Peptide Antibiotics

Kilianova,

Cizmarova,

Spaglova

et al. 2024

J of Separation Science

View full text Add to dashboard Cite

show abstract

Integrated identification-quantification (ID-Quant) workflow utilizing UPLC-QTOF-MS for the therapeutic drug monitoring of multi-component antibiotics without pure standards: Validation using teicoplanin

Ma,

Zou,

Zhong

et al. 2024

Journal of Chromatography B

View full text Add to dashboard Cite

A enzyme-free fluorescence quenching sensor for amplified detection of kanamycin in milk based on competitive triggering strategies

Bao,

Sang,

Yan

et al. 2024

RSC Adv.

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Therapeutic drug monitoring of glycopeptide antimicrobials: An overview of liquid chromatography-tandem mass spectrometry methods

Cited by 4 publications

References 83 publications

Recent Trends in Therapeutic Drug Monitoring of Peptide Antibiotics

Recent Trends in Therapeutic Drug Monitoring of Peptide Antibiotics

Integrated identification-quantification (ID-Quant) workflow utilizing UPLC-QTOF-MS for the therapeutic drug monitoring of multi-component antibiotics without pure standards: Validation using teicoplanin

A enzyme-free fluorescence quenching sensor for amplified detection of kanamycin in milk based on competitive triggering strategies

Contact Info

Product

Resources

About