Therapeutic Effect of Sodium Hyaluronate and Corticosteroid Injections on Pain and Temporomandibular Joint Dysfunction: A Quasi-experimental Study

Romero-Tapia, Percy; Pérez-Vargas, Fernando; Sedano-Balbin, Gabriela; Marín, Jorge Enrique Gómez; Mayta-Tovalino, Frank

doi:10.5005/jp-journals-10024-2890

Cited by 3 publications

(3 citation statements)

References 20 publications

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“…Good treatment results in the reports of Macedo De Sousa et al may result from simultaneous splint therapy [ 4 ]. Romero-Tapia et al describe a study to which they qualified only patients with a high degree of mandible mobility limitation, which could have contributed to the impressive treatment effect [ 35 ].…”

Section: Resultsmentioning

confidence: 99%

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The Administration of Hyaluronic Acid into the Temporomandibular Joints’ Cavities Increases the Mandible’s Mobility: A Systematic Review and Meta-Analysis

Chęciński¹,

Sikora

Chęcińska

et al. 2022

JCM

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Objectives: The purpose of this systematic review with meta-analysis is to identify clinical studies concerning the impact of intra-articular administration of hyaluronic acid (HA) on mandibular mobility and to make an attempt at determining the efficacy of HA in this indication. Methods: The review included primary studies involving groups of at least 10 patients who were diagnosed with pain in the temporomandibular joint and who were injected with hyaluronic acid as the only intervention. The outcomes pursued were changes in mandibular mobility and pain intensity. Four databases of medical articles were searched, including PubMed and BASE. The risk of bias was assessed using the Cochrane methodology tools. The therapy‘s efficacy was calculated in the domains of mandibular abduction, protrusive movement, lateral mobility, and pain relief. For these values, the regression and correlation with variables characterizing the interventions were analyzed. Results: In total, 16 reports on 20 study groups with a total of 1007 patients qualified for the review. The mean effectiveness in the domain of mandibular abduction over the 6-month follow-up period was 122% of the initial value, and the linear regression model can be expressed as 0.5x + 36. The level of pain in the same time frame decreased to an average of 29%. The severity of pain 6 months after the beginning of treatment positively correlates with the number of injections per joint (0.63), the total amount of drug administered in milliliters (0.62), and the volume of drug administered monthly per joint (0.50). Limitations: In some studies, the patient groups were heterogeneous in terms of diagnosis. The studies varied depending on the joint into which the HA was administered. The synthesized studies differed with regard to the method of measuring the mandible abduction amplitude. Conclusions: The increase in the amplitude of mandibular abduction was expressed as the quotient of the mean values during the observation periods, and the initial value was achieved in all study groups, and in the linear regression model, it was 0.5 mm on average per month. Multiple administrations of the drug may reduce the analgesic effectiveness of the treatment.

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Section: Resultsmentioning

confidence: 99%

“…Similar results were achieved by Bjørnland et al, who demonstrated much higher effectiveness of HA in pain relief compared to corticosteroids [ 29 ]. On the other hand, Romero-Tapia et al did not observe significant differences in the effectiveness of these therapies during the 2-month follow-up period [ 35 ].…”

Section: Discussionmentioning

confidence: 99%

The Administration of Hyaluronic Acid into the Temporomandibular Joints’ Cavities Increases the Mandible’s Mobility: A Systematic Review and Meta-Analysis

Chęciński¹,

Sikora

Chęcińska

et al. 2022

JCM

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“…CSs are definitely the best studied among them. After HA and PRP, CSs were the third most frequently reported injectables group in 2017-2022 (8 systematic reviews, 10 randomized trials, and 8 other trials) [19,25,38,39,41,45,47,47,49,51,54,62,75,86,121,125,127,134,135,137,140,156,164,166,171]. Nevertheless, since 2020, the number of primary studies on intra-articular injection of CSs has clearly decreased.…”

Section: Drugs Administrationmentioning

confidence: 99%

Current Clinical Research Directions on Temporomandibular Joint Intra-Articular Injections: A Mapping Review

Chęciński¹,

Chęcińska

Turosz

et al. 2023

JCM

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This mapping review aims to identify and discuss current research directions on intracavitary temporomandibular joints (TMJs) injections. The inclusion criteria allowed studies published in the last full six years, based on patients diagnosed with temporomandibular joint disorders (TMDs), treated by TMJ intra-articular injections. Medical databases covered by the Association for Computing Machinery, Bielefeld Academic Search Engine, PubMed, and Elsevier Scopus engines were searched. The results were visualized with tables, charts, and diagrams. Of the 2712 records identified following the selection process, 152 reports were qualified for review. From January 2017, viscosupplementation with hyaluronic acid (HA) was the best-documented injectable administered into TMJ cavities. However, a significant growing trend was observed in the number of primary studies on centrifuged blood preparations administrations that surpassed the previously leading HA from 2021.

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Efficacy of Arthrocentesis with and Without Sodium Hyaluronate Injection for Temporomandibular Joint Disorders: A Comparative Study

Sait¹,

Sequiera

Chandra

2023

J. Maxillofac. Oral Surg.

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Therapeutic Effect of Sodium Hyaluronate and Corticosteroid Injections on Pain and Temporomandibular Joint Dysfunction: A Quasi-experimental Study

Cited by 3 publications

References 20 publications

The Administration of Hyaluronic Acid into the Temporomandibular Joints’ Cavities Increases the Mandible’s Mobility: A Systematic Review and Meta-Analysis

The Administration of Hyaluronic Acid into the Temporomandibular Joints’ Cavities Increases the Mandible’s Mobility: A Systematic Review and Meta-Analysis

Current Clinical Research Directions on Temporomandibular Joint Intra-Articular Injections: A Mapping Review

Efficacy of Arthrocentesis with and Without Sodium Hyaluronate Injection for Temporomandibular Joint Disorders: A Comparative Study

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