Therapeutic Effects of Diagonal-Transcranial Direct Current Stimulation on Functional Recovery in Acute Stroke: A Pilot Study

Shibata, Takashi; Urata, Akio; Kawahara, Kazuyuki; Furuya, Kota; Ishikuro, Koji; Hattori, Noriaki; Kuroda, Satoshi

doi:10.1016/j.jstrokecerebrovasdis.2020.105107

Cited by 5 publications

(3 citation statements)

References 20 publications

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“…Moreover, it draws attention to a growing concern: the increasing incidence of IS and vascular comorbidities in individuals under 50 years of age. Such findings have the potential to shape health and education policies, including the prospect of introducing health education programs from an early age, for instance, in schools or as part of health education initiatives [ 33 ].…”

Section: Discussionmentioning

confidence: 99%

Stroke in Young Adults in Spain: Epidemiology and Risk Factors by Age

Pascasio

Blanco-Ruiz

Pinilla

et al. 2023

JPM

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Introduction: Recent research has highlighted an increased incidence of ischemic stroke (IS) in young adults, along with a higher percentage of vascular risk factors at younger ages. This study aimed to estimate the in-hospital incidence of IS and associated comorbidities by sex and age group in Spain. Methods: A retrospective analysis of the Spain Nationwide Inpatient Sample database from 2016 to 2019 was conducted, which included adult patients with IS. In-hospital incidence and mortality rates were estimated, and a descriptive analysis of the main comorbidities was performed, stratified by sex and age groups. Results: A total of 186,487 patients were included, with a median age of 77 (IQR 66–85) years and 53.3% were male. Of these, 9162 (5%) were aged between 18 and 50 years. The estimated incidence of IS in adults younger than 50 years ranged from 11.9 to 13.5 per 100,000 inhabitants during the study period, with a higher incidence in men. The overall in-hospital mortality was 12.6%. Young adults with IS had a higher prevalence of most vascular risk factors compared to the general Spanish population, with a specific distribution according to sex and age. Conclusions: This study provides estimates of the incidence of IS and the prevalence of vascular risk factors and comorbidities associated with IS in Spain, stratified by sex and age, using a national registry of hospital admissions. These findings should be considered in terms of both primary and secondary prevention strategies.

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Section: Discussionmentioning

confidence: 99%

Stroke in Young Adults in Spain: Epidemiology and Risk Factors by Age

Pascasio

Blanco-Ruiz

Pinilla

et al. 2023

JPM

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“…Although three to five days of tDCS has elicited large performance increases in simple motor tasks in young adults [ 5 , 18 , 19 ], it could be argued that as many as 9–40 days of tDCS could be needed to see an effect. Many studies in patient populations have utilized this range of stimulation sessions but have reported mixed results [ 34 , 35 , 36 ]. Third, interindividual differences in the responsiveness to DLPFC-tDCS could be at least partially responsible for the lack of observable performance enhancements.…”

Section: Discussionmentioning

confidence: 99%

The Influence of Transcranial Direct Current Stimulation on Shooting Performance in Elite Deaflympic Athletes: A Case Series

Pantović

Mačak

Čokorilo

et al. 2022

JFMK

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Transcranial direct current stimulation (tDCS) has been shown to improve motor learning in numerous studies. However, only a few of these studies have been conducted on elite-level performers or in complex motor tasks that have been practiced extensively. The purpose was to determine the influence of tDCS applied to the dorsolateral prefrontal cortex (DLPFC) on motor learning over multiple days on 10-m air rifle shooting performance in elite Deaflympic athletes. Two male and two female elite Deaflympic athletes (World, European, and National medalists) participated in this case series. The study utilized a randomized, double-blind, SHAM-controlled, cross-over design. Anodal tDCS or SHAM stimulation was applied to the left DLPFC for 25 min with a current strength of 2 mA concurrent with three days of standard shooting practice sessions. Shooting performance was quantified as the points and the endpoint error. Separate 2 Condition (DLPFC-tDCS, SHAM) × 3 Day (1,2,3) within-subjects ANOVAs revealed no significant main effects or interactions for either points or endpoint error. These results indicate that DLPFC-tDCS applied over multiple days does not improve shooting performance in elite athletes. Different stimulation parameters or very long-term (weeks/months) application of tDCS may be needed to improve motor learning in elite athletes.

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“…Transcranial direct current stimulation (tDCS) is a non-invasive neuromodulation technique that uses a constant low-intensity direct current (1~2 mA) to regulate the activity of cortical neurons [ 1 , 2 , 3 , 4 ]. In recent years, tDCS has been widely used in the clinical intervention and treatment of epilepsy [ 5 , 6 , 7 , 8 ], depression [ 9 , 10 ] stroke [ 11 , 12 ], and other neurological or psychiatric disorders [ 13 , 14 , 15 , 16 , 17 , 18 ]. Compared with other non-invasive brain stimulation techniques, tDCS has the advantages of high safety, good tolerance, convenient use, and less side effects [ 19 , 20 , 21 , 22 , 23 ].…”

Section: Introductionmentioning

confidence: 99%

A Novel Highly Durable Carbon/Silver/Silver Chloride Composite Electrode for High-Definition Transcranial Direct Current Stimulation

Cao

Duan³

2021

Nanomaterials

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High-definition transcranial direct current stimulation (HD-tDCS) is a promising non-invasive neuromodulation technique, which has been widely used in the clinical intervention and treatment of neurological or psychiatric disorders. Sintered Ag/AgCl electrode has become a preferred candidate for HD-tDCS, but its service life is very short, especially for long-term anodal stimulation. To address this issue, a novel highly durable conductive carbon/silver/silver chloride composite (C/Ag/AgCl) electrode was fabricated by a facile cold rolling method. The important parameters were systematically optimized, including the conductive enhancer, the particle size of Ag powder, the C:Ag:PTFE ratio, the saline concentration, and the active substance loading. The CNT/Ag/AgCl-721 electrode demonstrated excellent specific capacity and cycling performance. Both constant current anodal polarization and simulated tDCS measurement demonstrated that the service life of the CNT/Ag/AgCl-721 electrodes was 15-16 times of that of sintered Ag/AgCl electrodes. The much longer service life can be attributed to the formation of the three-dimensional interpenetrating conductive network with CNT doping, which can maintain a good conductivity and cycling performance even if excessive non-conductive AgCl is accumulated on the surface during long-term anodal stimulation. Considering their low cost, long service life, and good skin tolerance, the proposed CNT/Ag/AgCl electrodes have shown promising application prospects in HD-tDCS, especially for daily life scenarios.

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Therapeutic Effects of Diagonal-Transcranial Direct Current Stimulation on Functional Recovery in Acute Stroke: A Pilot Study

Cited by 5 publications

References 20 publications

Stroke in Young Adults in Spain: Epidemiology and Risk Factors by Age

Stroke in Young Adults in Spain: Epidemiology and Risk Factors by Age

The Influence of Transcranial Direct Current Stimulation on Shooting Performance in Elite Deaflympic Athletes: A Case Series

A Novel Highly Durable Carbon/Silver/Silver Chloride Composite Electrode for High-Definition Transcranial Direct Current Stimulation

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