Therapeutic hypothermia after cardiac arrest: A systematic review/meta-analysis exploring the impact of expanded criteria and targeted temperature

Schenone, Aldo L.; Cohen, Aarón; Patarroyo, Gabriel; Harper, Logan J.; Wang, Xiaofeng; Shishehbor, Mehdi H.; Menon, Venu; Duggal, Abhijit

doi:10.1016/j.resuscitation.2016.07.238

Cited by 80 publications

(44 citation statements)

References 43 publications

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“…One of the studies above was a high quality review and meta-analysis of nSR and TH [17] which included 2 RCTs [45] and [46] that was analyzed separately, also a non-RCT [22] was found in the search. Another more recent meta-analysis [29] included 11 trials of patients undergoing TH versus a control group which included both shockable and non-shockable rhythms. Most of the trials in their analysis had already been found in this search or were included in the previous meta-analysis that had been reviewed above [17].…”

Section: Resultsmentioning

confidence: 99%

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A review of the utility of a hypothermia protocol in cardiac arrests due to non-shockable rhythms

Freund

Kaplan

2017

Cardiol J.

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Section: Resultsmentioning

confidence: 99%

“…The effect of time down during arrest also was described in another trial with a cutoff noted at 10 min for improved outcomes [32]. Other studies also focused on variables affecting outcomes in TH/TTM-treated patients presenting with OHCA due to nSR [29,[34][35][36]39].…”

Section: Outcome Variablesmentioning

confidence: 99%

A review of the utility of a hypothermia protocol in cardiac arrests due to non-shockable rhythms

Freund

Kaplan

2017

Cardiol J.

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“…The recently updated Cochrane review on hypothermia for neuroprotection in adults after cardiopulmonary resuscitation, comparing conventional cooling versus no cooling, revealed a greater likelihood of reaching a favourable neurological outcome and survival benefit with cooling; however, it was also connected with increased incidence of pneumonia and hypokalaemia [25]. A recently published systematic review also indicated improved survival and neuroprotective benefit when exploring the impact of expended criteria and targeted temperature but did not find evidence to support one specific temperature over another [26].…”

Section: Discussionmentioning

confidence: 99%

Implementation of targeted temperature management after cardiac arrest in Polish intensive care units. What has changed in the last five years?

Krawczyk

Tarczynska²,

Dziadek³

et al. 2017

Kardiol Pol

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A b s t r a c tBackground: Studies conducted up to 2010 indicate the underuse of targeted temperature management (TTM) in Poland. Aim:This study evaluated the current degree of TTM implementation in Polish intensive care units (ICUs) and analysed the implementation process since 2010. Methods:A telephone survey, conducted from December 2014 to July 2015, was carried out to determine the number of ICUs using TTM in patients after cardiac arrest. We collected data on the details and prevalence of TTM, and the impact of organisational and financial issues and recently published papers on its use. Results:We obtained data from 271 of 396 ICUs (68.4%). In total, 79 (29.2%) ICUs indicated TTM use and 27 (34.2%) used dedicated TTM equipment. Overall, 62% of the ICUs used TTM regardless of the cardiac arrest rhythm. Target temperatures of 32-34°C and 34.1-36°C were reached by 44.3% and 43.0% of ICUs, respectively. The duration of TTM was 12-24 h in 58.2% of the ICUs. The most common barriers to TTM implementation were a lack of dedicated devices (36.3%) and organisational and logistical issues (31.2%). Any influence of recently published data on TTM practice modifications was reported by only 23.4% of the ICUs. Conclusions:Targeted temperature management is underused in Polish ICUs. There is a need for additional educational and implementation efforts supporting the translation of knowledge into clinical practice at the regional and national levels.

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“…He was sedated with midazolam and remifentanil and therapeutic hypothermia was initiated (33°C during a period of 24 hours) with cold infusion and a Blanketrol III (Cincinnati Sub-Zero Products) 2. On day 2, after reaching normothermia, the ECG had normalised and troponin levels were decreasing.…”

Section: Case Presentationmentioning

confidence: 99%

Cardiac arrest by inhalation of deodorant spray

Kramp¹,

Salih

Thomeer

et al. 2018

BMJ Case Reports

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Drug abuse by inhalation of volatile household product substances is uncommon, however, it can have devastating consequences. This case report describes the fatal outcome of deodorant inhalation by a 19-year-old patient in a detoxification clinic who developed a cardiac arrest after inhaling butane from a deodorant spray. Despite initial successful resuscitation, he developed a postanoxic encephalopathy with a status epilepticus resistant to extensive treatment. Inhalant abuse can be a cause of death in young patients.

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Therapeutic hypothermia after cardiac arrest: A systematic review/meta-analysis exploring the impact of expanded criteria and targeted temperature

Cited by 80 publications

References 43 publications

A review of the utility of a hypothermia protocol in cardiac arrests due to non-shockable rhythms

A review of the utility of a hypothermia protocol in cardiac arrests due to non-shockable rhythms

Implementation of targeted temperature management after cardiac arrest in Polish intensive care units. What has changed in the last five years?

Cardiac arrest by inhalation of deodorant spray

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