Therapeutic Hypothermia in STEMI

Bashtawi, Yazan; Almuwaqqat, Zakaria

doi:10.1016/j.carrev.2020.08.004

Cited by 6 publications

(2 citation statements)

References 67 publications

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“…20 Hypothermia therapy is believed to be beneficial to reperfusion injury by reducing the energy demand of myocardial cells. 21,22 It has a multifaceted impact on various signaling pathways involved in myocardial ischemia and reperfusion injury. 21,24 This distinguishes it from single-target approaches, such as pharmacological interventions, and makes it a promising treatment strategy.…”

Section: Hypothermia Therapy For Amimentioning

confidence: 99%

“…11,18,19 Hypothermia therapy is considered to have potential benefits in reducing reperfusion injury by reducing the energy demand of myocardial cells. [20][21][22][23][24] Supersaturated oxygen (SSO 2 ) therapy shows potential for improving oxygenation and minimize infarction size. [25][26][27][28][29] Inflammation targeting methods after AMI have promising results in animal trials, and a randomized controlled trial (RCT) the Colchicine cardiovascular outcomes trial (the COLCOT trial) has demonstrated the beneficial effects of colchicine.…”

Section: Introductionmentioning

confidence: 99%

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Recent advances in the diagnosis and management of acute myocardial infarction

Hsieh,

Wang,

Wang

et al. 2023

Journal of the Chinese Medical Association

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With the discovery of new biomarkers for the early detection of acute myocardial infarction (AMI), advancements in valid medication, and percutaneous coronary intervention (PCI), the overall prognosis of AMI has improved remarkably. Nevertheless, challenges remain which require more difficult work to overcome. Novel diagnostic and therapeutic techniques include new AMI biomarkers, hypothermia therapy, supersaturated oxygen (SSO2) therapy, targeted anti-inflammatory therapy, targeted angiogenesis therapy, and stem cell therapy. With these novel methods, we believe that the infarction size after AMI will decrease, and myocardial injury-associated ventricular remodeling may be avoided. This review focuses on novel advances in the diagnosis and management of AMI.

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