Therapeutic interventions to lessen the psychosocial effect of vitiligo in children: A review

Cadmus, Simi D.; Lundgren, Ashley D.; Ahmed, Ammar M.

doi:10.1111/pde.13517

Cited by 14 publications

(9 citation statements)

References 32 publications

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“…In various studies, coping strategies frequently discussed encompassed the utilization of concealing clothing, camouflage techniques and modified body movements. 54,55 Additional strategies comprised cognitive behavioural therapy and seeking psychological therapy or support through group settings. 56,57 Children and adolescents grappling with vitiligo commonly find themselves navigating a vital phase of psychological maturation.…”

Section: Ta B L Ementioning

confidence: 99%

Exploring genetic associations between vitiligo and mental disorders using Mendelian randomization

Wang,

Yao,

Lin

et al. 2023

Experimental Dermatology

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Although a large number of existing studies have confirmed that people with vitiligo are prone to mental disorders, these observational studies may be subject to confounding factors and reverse causality, so the true causal relationship is inconclusive. We conducted a bidirectional Mendelian randomization (MR) analysis to assess the causality between vitiligo and mental disorders, namely depression, anxiety, insomnia, schizophrenia, bipolar disorder, obsessive‐compulsive disorder (OCD) and attention‐deficit hyperactivity disorder (ADHD). Summary statistics from large available genome‐wide association study (GWAS) datasets for generalized vitiligo (n = 44 266), depression (n = 173 005), anxiety (n = 17 310), insomnia (n = 386 988), schizophrenia (n = 130 644), bipolar disorder (n = 413 466), OCD (n = 9725) and ADHD (n = 225 534) were utilized. Inverse‐variance weighted (IVW), MR‐Egger and weighted median were employed to estimate causal effects. Sensitivity analysis and MR Pleiotropy Residual Sum and Outliers (MR PRESSO) were conducted to assess heterogeneity and pleiotropy, ensuring the robustness of the results. Additionally, we corrected for estimating bias that might be brought on by sample overlap using MRlap. In our findings, none of the rigorous bidirectional MR analyses uncovered a significant causal association. Even after applying the MRlap correction, the effect sizes remained statistically nonsignificant, thereby reinforcing the conclusions drawn via IVW. In summary, our genetic‐level investigation did not reveal a causal link between generalized vitiligo and mental disorders.

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Section: Ta B L Ementioning

confidence: 99%

Exploring genetic associations between vitiligo and mental disorders using Mendelian randomization

Wang,

Yao,

Lin

et al. 2023

Experimental Dermatology

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“…Due to their skin condition, these patients may suffer from discrimination, stigmatization, bullying, fear of the risk of spreading illness, depression, interference in the process of socialization, and even sexual debut expectation. 45…”

Section: Vitiligomentioning

confidence: 99%

“…Finally, children and adolescents with vitiligo deserve particular attention because psychosocial distress can lead to a lifetime of mental health disorders like anxiety and depression. Due to their skin condition, these patients may suffer from discrimination, stigmatization, bullying, fear of the risk of spreading illness, depression, interference in the process of socialization, and even sexual debut expectation 45 …”

Section: Vitiligomentioning

confidence: 99%

Alterations in mental health and quality of life in patients with skin disorders: a narrative review

et al. 2021

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The presence of lesions in visible areas of skin may cause emotional troubles in patients, including low self‐worth, embarrassment, sorrow, and social isolation. Those alterations may predispose to psychiatric disorders such as anxiety, depression, and even suicidal ideation, severely affecting patients' health state and quality of life (QoL). In this article, we focus on dermatologic patients that present with secondary mental health alterations. Thus, we offer a detailed description of mental disorders observed in patients with acne vulgaris, atopic dermatitis, psoriasis, ichthyosis, vitiligo, and hidradenitis suppurativa. Moreover, we point out the relationship between the severity of the cutaneous symptoms with mental illnesses and QoL decline. Our objective was to highlight the importance of mental health care for patients with skin diseases. The impact of skin alterations on the mental health of dermatological patients should be a central concern. Likewise, the timely identification and treatment of mental disorders are essential for the comprehensive management of these skin diseases.

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“…Vitiligo and alopecia areata can be challenging for children’s mental and emotional health 1 . Both disorders disproportionately burden skin of color patients and parents due to the greater visibility of lesions in vitiligo, the additive impact of existing racial disparities, and racial barriers to in‐person care, such as traveling to appointments 2 .…”

Section: Figurementioning

confidence: 99%

Virtual group visits to reduce psychosocial distress and racial disparities in pediatric vitiligo and alopecia areata patients

Khosla

Grullon

Rosenblatt

2021

Pediatric Dermatology

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We examined the potential for virtual, pediatric group visits to reduce racial disparities in psychosocial isolation and access to care among children of color with pediatric vitiligo and alopecia areata as well as their caregivers. We have conducted 10 visits with 30 pediatric skin of color patients between 5 and 16 years old: 18 patients with alopecia areata, 12 with vitiligo, 59% female, 64% Black, and 23% Latinx, and 33 parents. After the visits, children and parents felt they had more people they knew and could reach out to about their dermatologic condition, the visits exceeded both children’s and parents’ expectations, and both children and parents reported that they would continue attending future group visits if offered. Group visits in the virtual format may present an opportunity for reducing racial disparities in psychosocial isolation and access to care across geographic locations in pediatric dermatology.

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Therapeutic interventions to lessen the psychosocial effect of vitiligo in children: A review

Cited by 14 publications

References 32 publications

Exploring genetic associations between vitiligo and mental disorders using Mendelian randomization

Exploring genetic associations between vitiligo and mental disorders using Mendelian randomization

Alterations in mental health and quality of life in patients with skin disorders: a narrative review

Virtual group visits to reduce psychosocial distress and racial disparities in pediatric vitiligo and alopecia areata patients

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