Therapeutic management in ambulatory elderly patients with atrial fibrillation: The S.AGES cohort

Abstract

In this elderly AF outpatient population, use of anticoagulant therapy was higher even after 80 years than in previous studies suggesting that recent international guidelines are better implemented in the elderly population.

Thromboembolic Risk, Bleeding Outcomes and Effect of Different Antithrombotic Strategies in Very Elderly Patients With Atrial Fibrillation: A Sub‐Analysis From the PREFER in AF ( PRE vention o F Thromboembolic Events– E uropean R egistry in A trial F ibrillation)

“…Results of our contemporary registry show that use of oral anticoagulant treatment in very elderly patients was still high (78%). This is consistent with other recent observational studies showing, in older AF populations, an improved penetration of chronic anticoagulant therapy . A different subanalysis from PREFER in AF was not focused on outcome results, but on the prevalence of different antithrombotic strategies in octagenarians; it showed that factors associated with oral anticoagulant utilization were previous ischemic stroke and heart failure, whereas higher age, previous bleeding, paroxysmal AF, chronic hepatic disease, lower autonomy, and problems for self‐care were associated with the nonuse of anticoagulant therapies.…”

Choice and Outcomes of Rate Control versus Rhythm Control in Elderly Patients with Atrial Fibrillation: A Report from the REPOSI Study

“…After several randomized trials found no difference between the rate-control and rhythm-control strategies for prognosis [7,8,19], a significant reduction in the use of rhythm-control management was evident, with rate control being the more widely used strategy [10,11,20,21]. Our data not only confirm previous evidence but also show, in a large contemporary 'real-world' cohort, that rate control remains the preferred management in elderly patients, with 83% of our cases being managed with rate-control drugs.…”

Age-Related Differences in the Clinical Characteristics and Treatment of Elderly Patients With Atrial Fibrillation in Japan ― Insight From the ANAFIE (All Nippon AF In Elderly) Registry ―

“…19, 21 Furthermore, available AF treatment guidelines do not provide specific information regarding the management of older patients. 22,23 Anticoagulants have been reported to be underused in the elderly, [24][25][26][27][28][29] and the presence of comorbidities further limited the use of anticoagulants in elderly patients. [29][30][31] The ANAFIE registry was designed to obtain real-world information on patients with NVAF aged ≥75 years, including current status, current anticoagulant therapy, and prognosis.…”