“…Additional work by this group produced a simple fluorescence-based assay to continuously monitor the activity of ornithine decarboxylase. 174 The enzyme catalyzed the transformation of lornithine to putrescine, which could be sensed by the combination of CB6 and the fluorogenic guest DSMI. This design is suitable for determination of inhibition constants, and for inhibitor HTS.…”
Duan and Y. Liu. W. Zhong directed the review layout design, coordinated the writing efforts, and prepared the sections of Introduction and outlook and opportunities sections.
“…Additional work by this group produced a simple fluorescence-based assay to continuously monitor the activity of ornithine decarboxylase. 174 The enzyme catalyzed the transformation of lornithine to putrescine, which could be sensed by the combination of CB6 and the fluorogenic guest DSMI. This design is suitable for determination of inhibition constants, and for inhibitor HTS.…”
Duan and Y. Liu. W. Zhong directed the review layout design, coordinated the writing efforts, and prepared the sections of Introduction and outlook and opportunities sections.
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