Therapeutic Modifications to the Mineral Ion Composition of Dental Plaque

Pearce, E.I.F.

doi:10.1159/000260757

Cited by 31 publications

(25 citation statements)

References 16 publications

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“…The fluoride concentrations of free smooth surface plaque collected after treatment [Birkeland et al, 1971;Pearce, 1984;Duckworth etal., 1987] are greater than those reported in this study. However, Wilson and Ashley [1988a, b] showed that significantly lower concentrations of inorganic ions are found in approx imal plaque compared to free smooth surface plaque of adolescents and young adults.…”

Section: Discussionmentioning

confidence: 99%

“…However, Birkeland et al [1971] showed a statistically significantly higher concentra tion of fluoride in plaque collected 4 h after rinsing from 8 subjects compared to plaque collected 24 h af ter rinsing from 12 other subjects. Pearce [1984] and Duckworth et al [1987] also showed significant in creases in the concentration of fluoride in plaque fol lowing the use of fluoride-containing mouthwashes.…”

mentioning

confidence: 94%

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Effect of Brushing with Fluoride Toothpastes on the Fluoride, Calcium, and Inorganic Phosphorus Concentrations in Approximal Plaque of Young Adults

Ad¹

1989

Caries Res

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A within-subject cross-over study was carried out to examine whether brushing with fluoride toothpastes would alter the composition of approximal plaque. Approximal plaque was collected from 22 subjects following brushing with toothpastes containing sodium fluoride and sodium monofluorophosphate with calcium glycerophosphate and a fluoride-free control toothpaste. Concentrations of plaque calcium, inorganic phosphorus, and fluoride were estimated. Toothbrushing with the fluoride toothpastes resulted in significantly greater concentrations of fluoride in approximal plaque when compared with the control toothpaste. However, there was no significant difference between the two fluoride toothpastes. The use of the sodium monofluorophosphate containing toothpaste resulted in significantly elevated concentrations of calcium and inorganic phosphorus in approximal plaque when compared to both sodium fluoride and control toothpastes. It was concluded that the use of a fluoride toothpaste can alter the chemical composition of approximal plaque.

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Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 94%

Effect of Brushing with Fluoride Toothpastes on the Fluoride, Calcium, and Inorganic Phosphorus Concentrations in Approximal Plaque of Young Adults

Ad¹

1989

Caries Res

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“…Dental plaque was dried for 16 h in vacuum at 40°C over P 2 O 5 [Pearce, 1984] and the dry weight was obtained using an analytical balance (B10 Ìg). For carbohydrate and inorganic analysis, 0.5 M HCl was added to the tube in the proportion of 0.25 ml/mg plaque dry weight.…”

Section: Biochemical Analysismentioning

confidence: 99%

Relationship among Dental Plaque Composition, Daily Sugar Exposure and Caries in the Primary Dentition

et al. 2002

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The relationship among daily sugar exposure, dental plaque composition and caries patterns in the primary dentition is not known. Three groups of 20 children (18–48 months old) were studied: (1) caries-free (CF), (2) presenting pit and fissure caries (PFC), and (3) with nursing caries (NC). Dental caries index (dmfs) was assessed and the frequency of daily sugar exposure (TS) and its forms were estimated by questionnaires. Fluoride (F), calcium (Ca), inorganic phosphorus (P_i), insoluble polysaccharide (IP) and mutans streptococci were quantified in dental plaque. The three groups of children were statistically different regarding daily sugar exposure. Concentrations of F, Ca and P_i were lower and the IP and mutans streptococci statistically higher in dental plaque from NC children than those from CF children. PFC children also showed statistically lower F and P levels in their plaque than CF children. Statistically significant correlations were found between IP, TS and dmfs from NC and PFC children. A statistically significant correlation between mutans streptococci in plaque from anterior teeth and dmfs for NC children was also observed. These results suggest that the dietary sugar experience changes the biochemical and microbiological composition of dental plaque, which could partly explain the different caries patterns observed in primary dentition.

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“…In principle, the chemical properties of this interface can be altered to decrease the cariogenic challenge originating from the metabolism of the oral flora. Several agents have been advanced as constituents of mouthwashes to minimize enamel demineralization, for example, lactate dehydrogenase [Higham and Edgar, 1991], urea and fluoride [Pearce, 1982[Pearce, , 1984Pearce and Nelson, 1988;Pearce et al, 1991], calcium phosphate [Stralfors, 1964;Rankine et al, 1989], calcium lactate [van der Hoeven, 1985;Shrestha et al, 1982;van der Hoeven et al, 1989;Kashket and Yaskell, 1992], calcium glycerophosphate [Bowen, 1972;Grenby and Bull, 1975;Sidi and Wilson, 1991] …”

mentioning

confidence: 99%

Comparative Reduction of Enamel Demineralization by Calcium and Phosphate in vitro

Tanaka¹,

Kadoma

2000

Caries Res

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In theory, calcium and phosphate in the plaque fluid exert a large influence on the demineralization of enamel surface. In order to know the effect of increasing the concentration of either of these factors, the following in vitro experiment was conducted. Three thin sections, about 150 Ìm thick, were cut out from each of 13 human premolars. All surfaces of the sections, except for the original enamel surface, were coated with nail varnish. These sections were immersed into one of two sets of demineralizing solutions for 1 week at 25°C. Each set, the ‘calcium set’ and the ‘phosphate set’, contained three solutions. The composition of these solutions differed mainly in calcium or phosphate concentrations. After 1 week, the degree of demineralization was determined by image analysis of contact microradiograms from each section. The subsurface demineralization in enamel was reduced by 95% by increasing the calcium concentration of the demineralizing solution from 7 to 21 mmol/l. A similar reduction (87%) was observed by increasing the phosphate concentration. However, the amount of phosphate needed was approximately 20 times more than that of calcium. The larger inhibitory effect that calcium has on enamel demineralization was related to the larger effect it has on the degree of saturation of the solution. Even though no statistically significant difference was found between the effect of calcium and phosphate on the demineralization of enamel (when the solutions had the same degree of saturation), the difference in the standard deviation of demineralization suggests the existence of some other factors which have an influence on the demineralization reaction.

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Therapeutic Modifications to the Mineral Ion Composition of Dental Plaque

Cited by 31 publications

References 16 publications

Effect of Brushing with Fluoride Toothpastes on the Fluoride, Calcium, and Inorganic Phosphorus Concentrations in Approximal Plaque of Young Adults

Effect of Brushing with Fluoride Toothpastes on the Fluoride, Calcium, and Inorganic Phosphorus Concentrations in Approximal Plaque of Young Adults

Relationship among Dental Plaque Composition, Daily Sugar Exposure and Caries in the Primary Dentition

Comparative Reduction of Enamel Demineralization by Calcium and Phosphate in vitro

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