Therapeutic polymers for dental adhesives: Loading resins with bio-active components

Abstract

Objectives Many recent adhesives on the market exhibit reasonable clinical performance. Future innovations in adhesive materials should therefore seek out novel properties rather than simply modifying existing technologies. It is proposed that adhesive materials that are “bio-active” could contribute to better prognosis of restorative treatments. Methods This review examines the recent approaches used to achieve therapeutic polymers for dental adhesives by incorporating bio-active components. A strategy to maintain adhesive restorations is the focus of this paper. Results Major trials on therapeutic dental adhesives have looked at adding antibacterial activities or remineralization effects. Applications of antibacterial resin monomers based on quaternary ammonium compounds have received much research attention, and the loading of nano-sized bioactive particles or multiple ion-releasing glass fillers have been perceived as advantageous since they are not expected to influence the mechanical properties of the carrier polymer. Significance The therapeutic polymer approaches described here have the potential to provide clinical benefits. However, not many technological applications in this category have been successfully commercialized. Clinical evidence as well as further advancement of these technologies can be a driving force to make these new types of materials clinically available.

Evaluation of selected properties of a new root repair cement containing surface pre-reacted glass ionomer fillers

“…Recently, various dental materials containing surface pre-reacted glass-ionomer fillers (S-PRG) were introduced by Shofu Inc. [11]. Multiple S-PRG-based dental materials are commercially available and have been collectively categorized as Giomer (Glass ionomer + polymer) [12].…”

Development of an Antibacterial Root Canal Filling System Containing MDPB

“…Many studies on various properties of the HEMA-based, light-cured self-etching primer containing 5% MDPB for composite restoration are available, including demonstration of its strong antibacterial activity against cariesrelated bacteria (Imazato et al, 1997(Imazato et al, , 2004(Imazato et al, , 2014Özer et al, 2003;Carvalho et al, 2012). It has also been reported, through in vitro and in vivo studies, that incorporation of MDPB into the lightcured primer up to 5% had no adverse influences on the bonding ability to dentin (Imazato et al, 1997(Imazato et al, , 2007.…”

Quaternary ammonium compounds in dental restorative materials

“…Moreover, adhesive containing quaternary ammonium antimicrobial monomer could kill residual bacteria quickly before curing, and play a role of pit and cavity disinfection 40) . It had contact inhibitory effect against the bacteria after curing, and prevented bacteria from invading the deep dentin through bonding interface, thus reducing the prevalence of secondary caries and prolonging the service life of the restoration 41) . Accordingly, Zhang et al 42) had studied the effects of QADM and NAg incorporation to an adhesive system, Scotchbond Multi-Purpose (SBMP).…”