Therapeutic potential of Camel Milk

Dubey, Uma S.; Lal, Madan; Mittal, Anyaa; Kapila, Suman

doi:10.9755/ejfa.2015-04-122

Cited by 27 publications

(9 citation statements)

References 64 publications

(101 reference statements)

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“…Since ancient times, it has also been used as a nutraceutical and therapeutic product in the population of the Middle East and some parts of Africa and Asia [ 35 ]. Camel milk is documented to possess properties that fight various diseases, including cancer, diabetes, autism, hypertension, and skin diseases [ 24 , 35 , 36 ]. This section discusses various health benefits obtained from camel milk and its products.…”

Section: Therapeutic Properties Of Camel Milkmentioning

confidence: 99%

Camels, Camel Milk, and Camel Milk Product Situation in Kenya in Relation to the World

Oselu

Ebere

Arimi

2022

International Journal of Food Science

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Kenya is the leading camel milk producer globally, with an annual production volume of 1.165 MMT, followed by Somalia (0.958 MMT) and Mali (0.271 MMT). In Kenya, pastoral tribes in North-Eastern parts rear about 4.722 million camels accounting for about 80% of all camels. Camels offer locals various benefits, including transportation of goods across the deserts, meat, fur, and milk. Camel milk contains natural therapeutically and immunity-boosting properties due to the higher concentration of lactoferrin, lactoglobulins, and lysozyme than bovine milk. Camel milk has been shown to have hypoallergenicity properties compared to bovine milk. Camel and human milk are similar in nutritional composition and therapeutic properties. Camel milk is known to fight various diseases, including cancer, diabetes, autism, hypertension, and skin diseases. Despite the standing of Kenya in the world in terms of camel milk production, Kenya lags considering the camel milk products, industries, and marketing. This paper reviews recent literature on camels and camel milk production trends in Kenya in relation to the world. The review also discusses various camel milk properties (nutritional and therapeutic) as well as the camel milk sector situation in Kenya.

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Section: Therapeutic Properties Of Camel Milkmentioning

confidence: 99%

Camels, Camel Milk, and Camel Milk Product Situation in Kenya in Relation to the World

Oselu

Ebere

Arimi

2022

International Journal of Food Science

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“…The unique characteristics of camel milk such as its therapeutic potential and absence β -LG have made it a focus area of research in the fields of health science and nutrition as an antimicrobial, antidiabetic and antihypertensive supplement. Camel milk is showing encouraging results in the treatment of autism, cancer, diabetes, and hepatitis and it is safe for children with bovine milk allergy [ 42 – 44 ].…”

Section: Functional Potential Of Camel Dairy Productsmentioning

confidence: 99%

Processing Challenges and Opportunities of Camel Dairy Products

Berhe

Seifu

Ipsen

et al. 2017

International Journal of Food Science

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A review on the challenges and opportunities of processing camel milk into dairy products is provided with an objective of exploring the challenges of processing and assessing the opportunities for developing functional products from camel milk. The gross composition of camel milk is similar to bovine milk. Nonetheless, the relative composition, distribution, and the molecular structure of the milk components are reported to be different. Consequently, manufacturing of camel dairy products such as cheese, yoghurt, or butter using the same technology as for dairy products from bovine milk can result in processing difficulties and products of inferior quality. However, scientific evidence points to the possibility of transforming camel milk into products by optimization of the processing parameters. Additionally, camel milk has traditionally been used for its medicinal values and recent scientific studies confirm that it is a rich source of bioactive, antimicrobial, and antioxidant substances. The current literature concerning product design and functional potential of camel milk is fragmented in terms of time, place, and depth of the research. Therefore, it is essential to understand the fundamental features of camel milk and initiate detailed multidisciplinary research to fully explore and utilize its functional and technological properties.

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“…Camel milk has been traditionally consumed worldwide for its nutritional benefits and medicinal properties. It also has therapeutic and prophylactic benefits against cancer (Dubey et al, 2016;Al haj and Al Kanhal, 2010). Camel milk proteins have more thermostability and pH hydrolysis resistance (Atri et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

Calcium chloride linked camel milk derived casein nanoparticles for the delivery of sorafenib in hepatocarcinoma cells

Mittal¹,

Mahala²,

Krishna³

et al. 2022

Biocell

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Sorafenib, a multikinase inhibitor used for the treatment of hepatocellular carcinoma, is limited by its low oral bioavailability. To overcome this drawback, we have developed novel camel milk casein-derived nanoparticles as a drug delivery system. Camel milk casein is not only biocompatible on oral administration but is actually a dietary protein of pharmaceutical relevance. Casein is used because of its amphiphilic nature, self-assembling property, ability to show sustained release, and capability of encapsulating both hydrophilic and hydrophobic drugs. In this study, camel milk casein nanoparticles loaded with sorafenib were developed and characterized. Characterization of casein nanoparticles was done by dynamic light scattering (DLS), zeta potential analysis, scanning light microscopy (SEM), and FTIR. The drug content in nanoparticle and drug-protein binding studies were conducted by UV spectroscopy. The cytotoxicity and cellular uptake efficiency studies were performed in HepG2 cell lines. It was observed that the cytotoxic effect of sorafenib loaded camel milk casein nanoparticles was more than free sorafenib in HepG2 cells. This work suggests camel milk casein as a suitable drug delivery molecule for sorafenib. In the future, it may also be used in enhancing the efficacy and specific distribution of other water-insoluble anticancer drugs.

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Therapeutic potential of Camel Milk

Cited by 27 publications

References 64 publications

Camels, Camel Milk, and Camel Milk Product Situation in Kenya in Relation to the World

Camels, Camel Milk, and Camel Milk Product Situation in Kenya in Relation to the World

Processing Challenges and Opportunities of Camel Dairy Products

Calcium chloride linked camel milk derived casein nanoparticles for the delivery of sorafenib in hepatocarcinoma cells

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