Therapeutic potential of wheatgrass (Triticum aestivum L.) for the treat-ment of chronic diseases

Sharma, Sachin; Shrivastav, Vivek Kumar; Shrivastav, Archana; Shrivastav, Braj Raj

doi:10.38150/sajeb.3(6).p308-313

Cited by 9 publications

(3 citation statements)

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“…29 Because of its rich chemical composition, it possesses a wide range of pharmacological actions like antioxidants, 30 blood generators, 31 blood purifiers, anti-inflammatory, 32 anti-arthritic, 33 analgesic, iron-chelating, 34 anticancer, 35 hepatoprotective, cardioprotective, 36 and many more. It is used in the treatment of neurological, gastrointestinal, hepato-biliary, endocrinological, hematological, cardiovascular, musculoskeletal, diabetes, 37 rheumatoid arthritis, 38 and dermatological disorders. 39 It is used in form of powder and fresh juice for thalassemia patients.…”

Section: Methodsmentioning

confidence: 99%

Phytochemical, Antioxidant, Toxicological, and Pharmaceutical Evaluation of Polyherbal Formulation: Irochel

2022

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Background and Purpose: Irochel is a polyherbal formulation, comprises ethanolic extracts of Emblica officinalis, Cucurbita pepo L, Triticum aestivum, Fagonia cretica, Momordica charantia, and Tribulus terristris. It is prepared for the management of iron overload in transfusion-dependent thalassemia patients in which non-transfusion binds iron-produced reactive oxygen species ROS that causes severe damages to the organs leads to death. Research Study: In this study, phytochemical, antioxidant-DPPH assay, cytotoxicity, acute, and subacute toxicity in Wistar rats according to OECD guidelines 423 and 407, respectively, was carried out. The pharmaceutical analysis was conducted following standard protocols. Results: The results exhibited that each herb has a rich amount of phytochemical constituents. The DPPH assay showed IC50 values for Irochel and Gallic Acid 106.6 ± 4.28 [uM] and 21.8 ± 1.03 [uM], respectively. The LC50 124.327 μg/ml was obtained in cytotoxicity. In acute toxicity (14 days) and subacute toxicity (28 days) studies, the results revealed no treatment-related toxic manifestations, or mortality. Therefore, LD50 was found > 5000 mg/kg. However, there was some hematological and biochemical variations observed at 3 different doses of 2000, 300, and 50 mg/kg bw. Conclusion: Thus, Irochel has significant antioxidant activity and it is a safe drug for human use.

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Section: Methodsmentioning

confidence: 99%

Phytochemical, Antioxidant, Toxicological, and Pharmaceutical Evaluation of Polyherbal Formulation: Irochel

2022

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“…Wheatgrass stands for young shoots of wheat, which are usually consumed in the form of fresh juice, but also in the form of powder or tablets. The high content of mineral, vitamins, enzymes, and chlorophyll and the high proportion of amino acids best express the rich chemical composition of wheatgrass [3][4][5]. Due to the listed biocomponents, research has shown that wheatgrass helps in the treatment of a number of diseases in humans, such as anemia [6,7] and ulcerative colitis [8], and also facilitates oncology patients' therapy [9,10].…”

Section: Introductionmentioning

confidence: 99%

Variation in Nutritional Value of Diverse Wheat Genotypes

Petrović,

Vila,

Grubišić Šestanj

et al. 2024

Agronomy

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Due to the health problems caused by the malnutrition of the world’s population, the focus of wheat breeding is turning to the improvement of the nutritional quality of wheat grain. Recently, the consumption of wheatgrass has become increasingly popular. The aim of this study was to determine the variability of total Mg, Fe, and Zn concentration, protein content, and phytic acid in wheat grains for a total of 93 genotypes. In addition, the variability of total and in vitro bioavailable concentrations of Mg, Fe, and Zn and protein content in the fresh juice of wheatgrass was investigated for the same 93 genotypes. The results obtained indicated significant variation in the phytate and nutrient compounds among examined wheat genotypes. In the grain, all examined traits significantly varied except Fe; the largest variability was found in phytate concentration (45.6%). In wheatgrass juice, the greatest variability was found for the in vitro bioavailable Zn (38.3%). Within wheat genotypes, outstanding values for some traits were detected, which could be used in breeding programs. The development of mineral-rich wheat genotypes depends on the identification of genetic resources with high levels of essential micronutrients and a better understanding of genotypic and environmental interactions.

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“…So far, the conventional approaches applied in aquaculture disease control mainly included the uses of antibiotics or other chemical agents (Sharma et al, 2012). However, the misuse of these chemical agents has resulted in antibiotic accumulation in aquatic products and increases of antibiotic-resistant bacteria in the environment (Cabello, 2006;Lulijwa et al, 2020).…”

Section: Introductionmentioning

confidence: 99%

The probiotic roles ofLactiplantibacillus plantarumE2 as a dietary supplement in growth promotion and disease resistance of juvenile large yellow croaker (Larimichthys crocea)

Ruizhe,

Shan,

Dongliang

et al. 2023

Preprint

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Bacterial diseases are the most important limiting factors for the development of large yellow croaker aquaculture. Probiotics are considered to be a promising alternative approach for the control of bacterial diseases in aquaculture. However, the studies on probiotics used in farmed large yellow croakers were very limited. In this study, we isolated and identified a Lactiplantibacillus plantarum E2 from the intestinal tract of large yellow croaker. L. plantarum E2 showed significant antibacterial activities against several aquaculture pathogenic bacteria, intestinal environmental tolerance, and biosafety. After 7 weeks of feeding, the E2 supplementation of dietary significantly improved the growth and the survival rates of large yellow croakers after Pseudomonas plecoglossicida PQLYC4 challenge. Further analysis showed that E2 effectively improved the intestinal integrity, and increased the intestinal α-amylase, trypsin and lipase activities. Moreover, the E2 supplementation also significantly suppressed the mRNA expression of IL-10 and increased the mRNA expression of IL-1β, IL-12α, IL-17D, IFN-γ, and TNF-α-R. Gut microbiota analysis showed that E2 significantly affected gut microbial community composition by decreasing the relative abundance of Sphingomonas and increasing the relative abundance of Lactobacillus and Pseudomonas. Finally, E2 could improve resistance of large yellow croaker against P. plecoglossicida PQLYC4 infection. Therefore, our findings showed that L. plantarum E2 has potential application as a probiotic in large yellow croaker, which may provide a new strategy of preventing and controlling bacterial diseases in this species.

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Therapeutic potential of wheatgrass (Triticum aestivum L.) for the treat-ment of chronic diseases

Cited by 9 publications

References 0 publications

Phytochemical, Antioxidant, Toxicological, and Pharmaceutical Evaluation of Polyherbal Formulation: Irochel

Phytochemical, Antioxidant, Toxicological, and Pharmaceutical Evaluation of Polyherbal Formulation: Irochel

Variation in Nutritional Value of Diverse Wheat Genotypes

The probiotic roles ofLactiplantibacillus plantarumE2 as a dietary supplement in growth promotion and disease resistance of juvenile large yellow croaker (Larimichthys crocea)

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