A wide spectrum of traditional medical methods employs Holarrhena floribunda (HF). A major source of novel pharmaceutically active compounds has always been plants. When it comes to treating disorders that do not respond well to synthetic medications, the modern medical system offers a wide range of herbal choices. There are a number of plants that have been used as medicine from ancient times to heal illnesses. Medicinal properties of herbal plants can be found in their chemical components. It is widely used in Togolese folk medicine as Holarrhena floribunda. False rubber tree, Holarrhena floribunda, belongs to the Apocynaceae family and may reach a height of 17 metres. Many components of the plant are used medicinally in West Africa. This plant has a variety of chemical components that are used to cure malaria, amoebic illness, diarrhoea, fever, infertility, and diabetes through the usage of plant parts including stem bark and leaves. In addition to highlighting Holarrhena floribunda's chemical composition, this paper also examines the plant's pharmacological properties.