Therapeutics within a Naturopathic Approach

Smith, Fraser

doi:10.1007/978-3-031-13388-6_6

Cited by 2 publications

(2 citation statements)

References 86 publications

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“…Additionally, the toxic effects are dose-dependent. The cancerogenic doses of methyleugenol in rodents following chronic exposure are approximately 1000-fold higher than the usual dietary intake of methyleugenol as a flavoring constituent in food [ 59 ]. According to the European Medicine Agency (EMA) report, the acute toxicity of this compound has not been fully investigated [ 44 ].…”

Section: Resultsmentioning

confidence: 99%

Echinophora tenuifolia subsp. sibthorpiana—Study of the Histochemical Localization of Essential Oil

Ivanova

Dyankov

Karcheva-Bahchevanska

et al. 2023

Molecules

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Background: Echinophora tenuifolia L. subsp. sibthorpiana is a perennial, aromatic plant used in traditional folk medicine and cuisine of the Mediterranean and the Middle East. However, scholars have not fully studied the pharmacological potential of the herb, and the scientific data on this plant species are limited. This study aimed to evaluate the chemical composition of the essential oil (EO) obtained from the aerial parts of E. tenuifolia subsp. sibthorpiana growing wild in Bulgaria and to perform histochemical analysis. Methods: A microscopic histochemical analysis and gas chromatography with mass spectrometry were performed. Results: The histochemical analysis confirmed the presence of terpenes in the stem and leaf of E. tenuifolia subsp. sibthorpiana. The phenylpropanoid methyleugenol was identified as the main compound in the EO, representing 48.13% of the total oil composition. There were also found considerable amounts of monoterpene hydrocarbons, representing 41.68% of the total EO. Alpha-phellandrene, o-cymene, and β-phellandrene were the most abundant monoterpene hydrocarbons. Conclusion: This is the first histochemical analysis performed on E. tenuifolia subsp. sibthorpiana. This is the first report of the EO composition from Bulgarian E. tenuifolia subsp. sibthorpiana, and our results indicate some future possibilities for evaluating of the biological activity of the EO of E. tenuifolia subsp. sibthorpiana and highlight the potential future use of the EO of this plant species. E. tenuifolia L. subsp. sibthorpiana EO possesses a good potential for use as a biopesticide and repellent an environmentally friendly alternative of synthetic pesticides.

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Section: Resultsmentioning

confidence: 99%

Echinophora tenuifolia subsp. sibthorpiana—Study of the Histochemical Localization of Essential Oil

Ivanova

Dyankov

Karcheva-Bahchevanska

et al. 2023

Molecules

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“…I propose that this plant species should be preserved by seed propagation; otherwise, it will be totally abolished if no action is taken [18] [19]. Mohammad et al [20] reported that the propagation of A. acuminata plant should be optimized through numerous plant growth regulator sources as this plant will be critically endangered [21]. So, to achieve this rationality, research is focused on highlighting this plant's worth as it is highly medicated.…”

Section: Introductionmentioning

confidence: 99%

Green Synthesis of Silver Atropa Acuminata Nanoparticles: Characterization and Anti-Diabetic Potential

Thakur,

Pandit

2023

J. Adv. Zool.

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Background: Atropa acuminata plant, which is also known as the maitbrand or Indian belladonna, belongs to the family Solanaceae and is closely related to the deadly nightshade of Europe and North Africa used in the treatment of various diseases. Objectives: The main objective is to investigate the antidiabetic potential of silver nanoparticles of Atropa acuminata. Methods: In this study green synthesis of silver nanoparticles was carried out. The current study engross the green synthesis of A. acuminata roots by reducing silver ions, where ultraviolet (UV) spectral analysis and transmission electron microscopy confirmed nanoarchitecture. The optimized silver nanoparticles were characterized for shape, size and morphological features by various techniques viz., SEM, TEM EDXA and XRD. The optimized formulation was further subjected for lipid peroxidation assay and in vitro antidiabetic assay in order to understand the antidiabetic potential of formulated silver nanoparticles. Results: The Silver nanoparticles of Atropa acuminata roots was successfully prepared by optimizing different concentration of plant extract at different temperatures and stirring speed. The Resultant optimized nanoparticles showed a particle size around 20 nm and -28 mv zeta potential. Further the characterization of optimized AgNPs was carried out. SEM provides the shape, size, and morphological features, whereas EDXA confirms the compositions and distribution of nanoparticles through spectrum and elemental mapping. XRD diffraction analysis revealed the crystalline structure of nanoparticles. Further, Nanoparticles showed a maximum scavenging potential of 82.633±0.116 for superoxide anion free radicals at 100 µg/mL concentration. Among two anti- diabetic assays, the αamylase assay shows a better result of percent inhibition 63 ± 1.32 at 75 μg/ml concentrations. Lastly, in vitro, drug release study revealed a 101.50% cumulative release from Ag- NPs formulation up to 1 hour, which was better than the standard one. Conclusion: This study explores the novel technology of green synthesis for various biomedical applications.

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Therapeutics within a Naturopathic Approach

Cited by 2 publications

References 86 publications

Echinophora tenuifolia subsp. sibthorpiana—Study of the Histochemical Localization of Essential Oil

Echinophora tenuifolia subsp. sibthorpiana—Study of the Histochemical Localization of Essential Oil

Green Synthesis of Silver Atropa Acuminata Nanoparticles: Characterization and Anti-Diabetic Potential

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