Therapy outcome in peritoneal dialysis patients transferred from haemodialysis

Liberek, Tomasz; Renke, Marcin; Skonieczny, Bartosz; Kotewicz, Karolina; Kowalewska, Jolanta; Chmielewski, Michael S.; Kot, Jacek; Lichodziejewska‐Niemierko, Monika; Rutkowski, Bolesław

doi:10.1093/ndt/gfp132

Cited by 36 publications

(32 citation statements)

References 16 publications

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“…3 PDI Our study also suggests that technique survival in transfer and no-transfer patients was similar. That finding is consistent with a previously reported study (6); however, other investigations revealed that technique survival was lower in transferred patients (18,19). Whether a history of HD therapy can or cannot influence peritoneal membrane function is still beyond our knowledge, but some evidence still indirectly favors our results to some extent.…”

Section: Discussionsupporting

confidence: 94%

Clinical Outcomes of Peritoneal Dialysis Patients Transferred from Hemodialysis: A Matched Case–Control Study

Zhang

Cao

et al. 2012

Perit Dial Int

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♦ Objective: Our study aimed to evaluate clinical outcomes of patients transferred to peritoneal dialysis (PD) because of complications related to hemodialysis (HD). ♦ Methods: In a 1:2 matched case-control study, we compared patient and technique sur vival between patients initially treated with HD for at least 3 months and then transferred to PD (transfer group) and patients started on and continuing with PD (notransfer group).

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Section: Discussionsupporting

confidence: 94%

Clinical Outcomes of Peritoneal Dialysis Patients Transferred from Hemodialysis: A Matched Case–Control Study

Zhang

Cao

et al. 2012

Perit Dial Int

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“…These causes may be biologic or a result of unmeasured and/or unaccounted bias. Often, a switch from PD to HD relates to the technique failure, whereas problems with vascular access, higher risk of cardiovascular disease, or personal preference are commonly cited when HD patients switch to PD (21,22). In our study, patients with the same transplantation status had similar characteristics regardless of whether they changed an initial modality (Table 1).…”

Section: Discussionmentioning

confidence: 75%

Comparing Mortality of Peritoneal and Hemodialysis Patients in the First 2 Years of Dialysis Therapy

Lukowsky

Mehrotra

Kheifets

et al. 2013

Clinical Journal of the American Society of Nephrology

149

101

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SummaryBackground and objectives There are conflicting research results about the survival differences between hemodialysis and peritoneal dialysis, especially during the first 2 years of dialysis treatment. Given the challenges of conducting randomized trials, differential rates of modality switch and transplantation, and time-varying confounding in cohort data during the first years of dialysis treatment, use of novel analytical techniques in observational cohorts can help examine the peritoneal dialysis versus hemodialysis survival discrepancy.Design, setting, participants, & measurements This study examined a cohort of incident dialysis patients who initiated dialysis in DaVita dialysis facilities between July of 2001 and June of 2004 and were followed for 24 months. This study used the causal modeling technique of marginal structural models to examine the survival differences between peritoneal dialysis and hemodialysis over the first 24 months, accounting for modality change, differential transplantation rates, and detailed time-varying laboratory measurements.Results On dialysis treatment day 90, there were 23,718 incident dialysis-22,360 hemodialysis and 1,358 peritoneal dialysis-patients. Incident peritoneal dialysis patients were younger, had fewer comorbidities, and were nine and three times more likely to switch dialysis modality and receive kidney transplantation over the 2-year period, respectively, compared with hemodialysis patients. In marginal structural models analyses, peritoneal dialysis was associated with persistently greater survival independent of the known confounders, including dialysis modality switch and transplant censorship (i.e., death hazard ratio of 0.52 [95% confidence limit 0.34-0.80]).Conclusions Peritoneal dialysis seems to be associated with 48% lower mortality than hemodialysis over the first 2 years of dialysis therapy independent of modality switches or differential transplantation rates.

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“…21 PD requires a significant patient compliance, family support, and a clear understanding about the application technique. As the first choice of treatment modality, PD should be applied treatment under suitable conditions.…”

Section: Discussionmentioning

confidence: 99%

Factors Associated with Above and Under 5-Year Survival in Peritoneal Dialysis Patients

Ünsal¹,

Baştürk²,

Koç³

et al. 2012

Renal Failure

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Background/aims: A few patients stay on peritoneal dialysis (PD) for 5 years or longer from initiation of therapy. We investigated patient survival and factors affecting mortality in PD patients. Methods: This was a retrospective study including 354 PD patients. The demographic, clinical, and biochemical data were collected from the medical records. Two hundred patients were excluded. Evaluation was carried out on data from 154 patients, including 83 surviving 5 years or more and 71 who were taken as surviving less than 5 years. Results: Mean age, number of comorbid diseases, prevalence of diabetes mellitus (DM), rate of mandatory preference of PD, making their PD exchanges with help from anyone were lower in surviving patients, and education level was higher in surviving patients. Advanced age, high rate of mandatory preference of PD, high rate of baseline high, and high-average peritoneal transporters were associated with an increased risk of death. Conclusion: Long-term survival is possible for PD patients, particularly nondiabetics, those having higher education level, those with a self-preference of PD, and those making PD exchanges without any help.

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Therapy outcome in peritoneal dialysis patients transferred from haemodialysis

Cited by 36 publications

References 16 publications

Clinical Outcomes of Peritoneal Dialysis Patients Transferred from Hemodialysis: A Matched Case–Control Study

Clinical Outcomes of Peritoneal Dialysis Patients Transferred from Hemodialysis: A Matched Case–Control Study

Comparing Mortality of Peritoneal and Hemodialysis Patients in the First 2 Years of Dialysis Therapy

Factors Associated with Above and Under 5-Year Survival in Peritoneal Dialysis Patients

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