Thermal ablation by high-intensity-focused ultrasound using a toroidal transducer for the treatment of colorectal liver metastases during an open procedure. Clinical results

Melodelima, David; Vincenot, Jérémy; Chen, Yao; Dupré, Aurélien; Rivoire, Michel; Chapelon, Jean‐Yves

doi:10.1121/1.4805953

The Journal of the Acoustical Society of America

2013

DOI: 10.1121/1.4805953

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Thermal ablation by high-intensity-focused ultrasound using a toroidal transducer for the treatment of colorectal liver metastases during an open procedure. Clinical results

David Melodelima

Jérémy Vincenot

Yao Chen

et al.

Abstract: Lesions 3aBAb2. Thermal ablation by high-intensity-focused ultrasound using a toroidal transducer for the treatment of colorectal liver metastases during an open procedure. Clinical results

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“…Interventional radiologic options in liver tumors include embolization and ablative techniques (19)(20)(21)(22)(23)(24). Data from studies on RF ablation in primary hepatocellular carcinoma suggest that RF ablation is effective in this disease and has several advantages, as it can be used repeatedly and has a low sideeffect profile (7,8,25).…”

mentioning

confidence: 99%

Radiofrequency Ablation for Neuroendocrine Liver Metastases: A Systematic Review

Mohan¹,

Nicholson²,

Winter³

et al. 2015

Journal of Vascular and Interventional Radiology

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mentioning

confidence: 99%

Radiofrequency Ablation for Neuroendocrine Liver Metastases: A Systematic Review

Mohan¹,

Nicholson²,

Winter³

et al. 2015

Journal of Vascular and Interventional Radiology

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High Intensity Focused Ultrasound Technology, its Scope and Applications in Therapy and Drug Delivery

Phenix

Togtema²,

Pichardo³

et al. 2014

J Pharm Pharm Sci

125

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Ultrasonography is a safe, inexpensive and wide-spread diagnostic tool capable of producing real-time non-invasive images without significant biological effects. However, the propagation of higher energy, intensity and frequency ultrasound waves through living tissues can induce thermal, mechanical and chemical effects useful for a variety of therapeutic applications. With the recent development of clinically approved High Intensity Focused Ultrasound (HIFU) systems, therapeutic ultrasound is now a medical reality. Indeed, HIFU has been used for the thermal ablation of pathological lesions; localized, minimally invasive ultrasound-mediated drug delivery through the transient formation of pores on cell membranes; the temporary disruption of skin and the blood brain barrier; the ultrasound induced break-down of blood clots; and the targeted release of drugs using ultrasound and temperature sensitive drug carriers. This review seeks to engage the pharmaceutical research community by providing an overview on the biological effects of ultrasound as well as highlighting important therapeutic applications, current deficiencies and future directions.This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.

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Thermal ablation by high-intensity-focused ultrasound using a toroidal transducer for the treatment of colorectal liver metastases during an open procedure. Clinical results

Abstract: Lesions 3aBAb2. Thermal ablation by high-intensity-focused ultrasound using a toroidal transducer for the treatment of colorectal liver metastases during an open procedure. Clinical results

Cited by 2 publications

References 20 publications

Radiofrequency Ablation for Neuroendocrine Liver Metastases: A Systematic Review

Radiofrequency Ablation for Neuroendocrine Liver Metastases: A Systematic Review

High Intensity Focused Ultrasound Technology, its Scope and Applications in Therapy and Drug Delivery

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