Thermal analysis and characterisation of cellulose grafted with acrylic monomers

Princi, Elisabetta; Vicini, Silvia; Pedemonte, Enrico; Mulas, Alessandro; Franceschi, E.; Luciano, Giorgio; Trefiletti, Vincenzo

doi:10.1016/j.tca.2004.07.001

Cited by 81 publications

(50 citation statements)

References 18 publications

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“…The first broad peak at about 70°C is related to water evaporation, while the second endothermic peak in the 110°C-130°C range is connected to the glass transition temperature of water-plasticized chitosan macromolecules. 18 Chitosan nanobubbles showed a T peak at 124.6°C, while the chitosan solution showed a T peak at 114.7°C. The melting temperatures differed from those of a pH 5.0 reference chitosan solution (of the same polymer concentration), reflecting a change in the polysaccharide matrix in the nanobubble structure.…”

Section: Resultsmentioning

confidence: 93%

New chitosan nanobubbles for ultrasound-mediated gene delivery: preparation and in vitro characterization

Cavalli¹,

Bisazza²,

Trotta³

et al. 2012

IJN

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Background:The development of nonviral gene delivery systems is one of the most intriguing topics in nanomedicine. However, despite the advances made in recent years, several key issues remain unsettled. One of the main problems relates to the difficulty in designing nanodevices for targeted delivery of genes and other drugs to specific anatomic sites. In this study, we describe the development of a novel chitosan nanobubble-based gene delivery system for ultrasound-triggered release. Methods and results: Chitosan was selected for the nanobubble shell because of its low toxicity, low immunogenicity, and excellent biocompatibility, while the core consisted of perfluoropentane. DNA-loaded chitosan nanobubbles were formed with a mean diameter of less than 300 nm and a positive surface charge. Transmission electron microscopic analysis confirmed composition of the core-shell structure. The ability of the chitosan nanobubbles to complex with and protect DNA was confirmed by agarose gel assay. Chitosan nanobubbles were found to be stable following insonation (2.5 MHz) for up to 3 minutes at 37°C. DNA release was evaluated in vitro in both the presence and absence of ultrasound. The release of chitosan nanobubble-bound plasmid DNA occurred after just one minute of insonation. In vitro transfection experiments were performed by exposing adherent COS7 cells to ultrasound in the presence of different concentrations of plasmid DNA-loaded nanobubbles. In the absence of ultrasound, nanobubbles failed to trigger transfection at all concentrations tested. In contrast, 30 seconds of ultrasound promoted a moderate degree of transfection. Cell viability experiments demonstrated that neither ultrasound nor the nanobubbles affected cell viability under these experimental conditions. Conclusion: Based on these results, chitosan nanobubbles have the potential to be promising tools for ultrasound-mediated DNA delivery.

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Section: Resultsmentioning

confidence: 93%

New chitosan nanobubbles for ultrasound-mediated gene delivery: preparation and in vitro characterization

Cavalli¹,

Bisazza²,

Trotta³

et al. 2012

IJN

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“…It is evident from The counter reading at peak intensity at 22˚ is said to represent the crystalline material and the peak intensity at 18˚ corresponds to the amorphous material in cellulose [60,61] , Percentage Crystallinity [62] and crystalline index [63,64] were calculated and tabulated in Table 4. A poor crystallinity index in case of untreated hemp fibers reinforced in cellulose filled epoxy matrix means poor order of cellulose crystals to the fiber axis during treatments, indicated by the lower crystallinity index.…”

Section: X-ray Diffraction Analysismentioning

confidence: 99%

Dynamic mechanical analysis and crystalline analysis of hemp fiber reinforced cellulose filled epoxy composite

et al. 2017

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“…The results are presented in Table I. Percentage polymer loading (%PL), percentage graft yield (%GY), and percentage grafting efficiency (%GE) formed were calculated by using following methods: 25 Percentage polymer loading (% PL)…”

Section: Graft Copolymerizationmentioning

confidence: 99%

Microwave‐enhanced synthesis of graft copolymer of binary vinyl monomer mixtures onto acetylated Saccharum spontaneum L and characterization

et al. 2011

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Synthesis of graft copolymer under the influence of microwave radiation is a rapid, efficient, clean, cheap, convenient, energy-saving, and green method. Grafting of methylmethacrylate (MMA) + acrylamide (AAm), MMA + acrylonitrile (AN), and MMA + acrylic acid (AA) binary mixtures onto acetylated Saccharum spontaneum L was carried out under the influence of microwave radiation (MWR), and maximum graft yield 94.5% was found with MMA + AAm binary mixture. Synthesized graft copolymers were characterized with FT-IR,

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Thermal analysis and characterisation of cellulose grafted with acrylic monomers

Cited by 81 publications

References 18 publications

New chitosan nanobubbles for ultrasound-mediated gene delivery: preparation and in vitro characterization

New chitosan nanobubbles for ultrasound-mediated gene delivery: preparation and in vitro characterization

Dynamic mechanical analysis and crystalline analysis of hemp fiber reinforced cellulose filled epoxy composite

Microwave‐enhanced synthesis of graft copolymer of binary vinyl monomer mixtures onto acetylated Saccharum spontaneum L and characterization

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