The increasing concerns about CO2 emissions and climate change have pointed out the urgency of promoting sustainability in the building sector. One promising solution to enhance the energy efficiency of buildings and diminish environmental impact is the integration of phase-change materials (PCMs) into ventilated façade systems. This review article critically examines the current state of research on this innovative approach, with a particular focus on fire safety considerations. The paper explores the integration of PCM into ventilated façades, highlighting the potential for significant improvements in energy consumption, thermal comfort, and reductions in CO2 emissions. However, the flammability of PCMs introduces substantial fire safety challenges that must be addressed to ensure the safe application of this solution. The fire safety of both ventilated façades and PCMs is approached, followed by specific fire safety concerns when PCMs are integrated into ventilated façade systems. The conclusion states that while the integration of PCMs into ventilated façades offers substantial environmental benefits, attention to fire safety is essential. This necessitates the implementation of rigorous fire protection measures during the design and construction phases. By addressing both the environmental advantages and fire safety challenges, this review aims to provide a comprehensive understanding of the potential and limitations of PCM-integrated ventilated façades, offering valuable insights for researchers, engineers, and policymakers in the field of sustainable buildings.