Over 200 million motorcycles in use worldwide account for a substantial portion of global mobile source total hydrocarbons (THC) and carbon monoxide (CO) emissions. In Tehran, capital of Iran, ultrarich inefficient combustion in gasolinefueled motorcycles results in significantly high CO and THC emissions. Motorcycle catalysts can reduce CO and C 3 H 6 (as a representative hydrocarbon) emission factors by 60−80%. In the present work, CO and propylene oxidation over a commercial Pt− Pd-based wiremesh catalyst is studied in a flow reactor setup under simulated conditions relevant to 125 cc four-stroke gasoline carburetor motorcycles. Steady-state individual and co-oxidation tests for CO and C 3 H 6 oxidation under rich, stoichiometric, and lean conditions indicated that increasing oxygen concentration shifted the light-off profile toward lower temperatures. Kinetics of CO and C 3 H 6 oxidation were studied. For co-oxidation of CO and C 3 H 6 , the apparent activation energies of CO and C 3 H 6 oxidation were decreased by increasing oxygen concentration, indicating the positive role of oxygen in the reaction progress. The obtained reaction orders indicated the self-and mutual-inhibition effects of CO and C 3 H 6 . The highly positive order for O 2 confirmed the beneficial effect of oxygen. Our results suggest that injecting secondary air in the motorcycle exhaust gas can be used as a practical technique for enhancing CO and hydrocarbon oxidation efficiency over a Pt−Pd/CeO 2 −ZrO 2 −Al 2 O 3 wiremesh catalyst.