In this study numerical solutions for magnetohydrodynamic transfer, thermal and mass instability, free convection flow through the plate before Casson fluid, heat dissipation, thermal radiation, heat sink, chemical reaction, tilt angle, and saturated porous medium were described. The effectiveness of this study is to analyze the effect of heat diffusion, Casson fluid, the angle of interest on the flow phenomenon of Cu-nanoparticles in the presence of thermal radiation, heat source/heat sink, destructive reaction, heat transfer and mass transfer in a simple way. The finite difference method was used to solve the governing equations which are the added partial differential equations. The effects of different material parameters on velocity, temperature and concentration profiles are explained using graphs and tables. The results are compared with previously published papers and a very good agreement is found. In the boundary layer region, fluid velocity decreases with the increasing values of magnetic field parameter, heat source/sink, Casson fluid, angle of inclination and thermal radiation parameter for Cu-nanoparticles. Also it is noticed that the solutal boundary layer thickness decreases with an increase in the chemical reaction parameter. It is because chemical molecular diffusivity reduces for higher values of Kr.