“…To tackle this challenge, various approaches of Uncertainty Analysis (UA) have been developed, e.g., Code Scaling, Applicability, and Uncertainty (CSAU) [Boyack et al 1990] [Wilson et al 1990] [Wulf et al 1990], Automated Statistical Treatment of Uncertainty Method (ASTRUM), Integrated Methodology for Thermal-Hydraulics Uncertainty Analysis (IMTHUA) [Pourgol-Mohammad 2009], which assume that the uncertainty in the input variables follows a statistical distribution: N input sets are sampled and fed to the BE code and the corresponding N output values are calculated, which reflect the variability of the input variables onto the output. A combination of Order Statistics (OS) [Guba et al 2003] [Zio et al 2008] and Artificial Neural Networks (ANN) has been proposed to speed up computation (substituting the TH code with a simpler and faster surrogate) [Secchi et al 2008].…”