Thermal, mechanical and functional properties of cellulose acetate phthalate (CAP) coatings obtained from neutralized aqueous solutions

Flavonoids as Anti-Inflammatory and Analgesic Drugs: Mechanisms of Action and Perspectives in the Development of Pharmaceutical Forms

“…Cellulose acetate phthalate (CAP) was as insoluble and stable in acidic gastric fluid as in its nonionized form. It becomes soluble, swellable, and disintegrable as the phthalic acid groups ionized above pH 6 in intestinal fluid [143]. However, these results showed that satisfactory, gastro-resistant microsystems were produced only for the more soluble glycosides, such as rutin and naringin [142,144].…”

Study of high amylose corn starch as food grade enteric coating in a microcapsule model system

“…In drugs, this challenge is usually overcome by the use of enteric coating. Commonly used enteric coating materials for drug delivery are natural (Mueller & Yunis-Specht, 1994;Tokunaga, 2001;Okubo, 2001;Toyama, Mizota, Asano & Iiyama, 2001;Miyazaki, Kamakura & Fukushima, 2001), semi synthetic (Schmidt & Niemann, 1992;Doi, Hirota, Yoshida & Takahashi, 1993;Bechard, Levy & Clas, 1995;Williams & Liu, 2000), and synthetic polymers (Plaizier-Vercammen & Van Molle, 1991;Wilding, Davis & O'Hagan, 1994;Felton et al, 1995;Semde, Amighi, Devleeschou-*Corresponding author. Tel.…”

Structure and properties of maize starch processed with a combination of α-amylase and pullulanase

“…The coatings of such compounds should be based on materials stable in both the stomach and small intestine environments in order to reach the colon intact, and should have the ability to release the active ingredient in these areas. Commonly used enteric coating materials include shellac and zein, amylose acetate phthalate, cellulose derivatives [2,3], and methylmethacrylate polymers [4]. Most of these materials are susceptible to pH changes.…”