In the Present study, the steady flow and heat transfer of Casson fluid from a permeable horizontal cylinder in the presence of slip condition in a non-Darcy porous medium is analyzed. The cylinder surface is maintained at a constant temperature. The boundary layer conservation equations, which are parabolic in nature, are normalized into non-similar form and then solved numerically with the well-tested, efficient, implicit, stable Keller-box finite-difference scheme. Increasing the velocity slip parameter is found to decrease the velocity and boundary layer thickness and increases the temperature and the boundary layer thickness. The velocity decreases with the increase the non-Darcy parameter and is found to increase the temperature. The velocity increases with the increase the Casson fluid parameter and is found to decrease the temperature. The Skin-friction coefficient and the local Nusselt number are found to decrease with the increase in velocity and thermal slip parameters respectively. Volume 2 • Issue 2 • 1000127 J Appl Computat Math ISSN: 2168-9679 JACM, an open access journal structural characteristics of many important liquids including polymer suspensions, liquid crystal melts, physiological fluids, contaminated lubricants, etc.The steady flow of non-Newtonian fluids in the presence of heat transfer is an important research area due to its wide use in food processing, power engineering, and petroleum production and in many industries for example polymers melt and polymer solutions employed in the plastic processing. Several fluids in chemical engineering, multiphase mixtures, pharmaceutical formulations, china clay and coal in water, paints, synthetic lubricants, salvia, synovial fluid, jams, soups, jellies, marmalades, sewage sludge etc are non-Newtonian. The constitutive relations for these kinds of fluids give rise to more complex and higher order equations than the Navier-Stokes equations. Considerable progress even through has been made on the topic by using different models of non-Newtonian fluids [2][3][4][5][6][7][8][9][10][11].