Thermal rearrangement of an N-hydroxy-imidazole thiocarbamoyl derivative as a simple entry into the 4-thio-imidazole motif

Abstract

A thermal rearrangement of a thio-ester derivative of N-hydroxyimidazole gives rise, in a clean reaction, to the corresponding 4-and 2-thiol ester derivatives in a 1 : 1 ratio.