Quantum tunneling of vortices had been found to be an important novel phenomena for description of low temperature creep in high temperature superconductors (HTSCs). We speculate that quantum tunneling may be also exhibited in mesoscopic superconductors due to vortices trapped by the Bean-Livingston barrier. The London approximation and method of images is used to estimate the shape of the potential well in superconducting HTSC quantum dot. To calculate the escape rate we use the instanton technique. We model the vortex by a quantum particle tunneling from a two-dimensional ground state under magnetic field applied in the transverse direction. The resulting decay rates obtained by the instanton approach and conventional WKB are compared revealing complete coincidence with each other.