In this article, thermal buckling analysis of multilayer functionally graded graphene platelets (FGGPL) strengthened piezoelectric beam subjected to external electric voltage as well as humid conditions is illustrated. The effective Young’s modulus of the nanocomposite beam is estimated within the framework of Halpin-Tsai model. While, Poisson’s ratio, mass density, and piezoelectric properties are calculated by the rule of the mixture. Four FGGPL distribution types are considered in this study. A refined two-unknown beam theory considering shear deformation as well as thickness stretching effect is employed to describe the displacement components. The principle of virtual work including thermal, moisture, and electric loads is used to derive the stability differential equations. To check the accuracy of the obtained buckling temperature, some comparison examples are performed. The impacts of the GPLs volume fraction, distribution type, length-to-depth ratio, humid conditions, external electric voltage, and piezoelectric properties on the critical buckling temperature are studied.