In this paper, a numerical model is developed to simulate the ballistic impact of a projectile on a sandwich panel with honeycomb core and composite skin. To this end, a suitable material model for the aluminum honeycomb core is used taking the strain-rate dependent properties into account. To validate the ballistic impact of the projectile on the honeycomb core, numerical results are compared with the experimental results available in literature and ballistic limit velocities are predicted with good accuracy. Moreover, to achieve composite skin material model, a VUMAT subroutine including damage initiation based on Hashin’s seven failure criteria and damage evolution based on MLT approach modulus degradation is used. To validate the composite material model VUMAT subroutine, the ballistic limit velocities of the projectile impact on the composite laminates are predicted similar to the numerical results presented by other researchers. Next, the numerical model of the sandwich panel ballistic impact at different velocities is compared with the available experimental results in literature, and energy absorption capacity of the sandwich panel is predicted accurately. In addition, the numerical model simulated the sandwich panel damage mechanisms in different stages similar to empirical observations. Also, the composite skin damages are investigated based on different criteria damage contours.