Thermo-optical characterization of fluorescent rhodamine B based temperature-sensitive nanosensors using a CMOS MEMS micro-hotplate

Chauhan, Veeren M.; Hopper, Richard; Ali, Syed Zeeshan; King, Emma; Udrea, F.; Oxley, C. H.; Aylott, Jonathan W.

doi:10.1016/j.snb.2013.10.042

Cited by 54 publications

(36 citation statements)

References 40 publications

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“…In order to achieve stable and reliable results, the certain balance between isolation and overlap of the probe with the environment is desired. This could be achieved, for example, by embedding dyes in polymer or inorganic host matrix to control their interaction with surrounding environment [16,17]. Phase transitions sensing in a host media is one among other interesting applications of molecular probes.…”

Section: Introductionmentioning

confidence: 99%

Temperature and Phase Transition Sensing in Liquids with Fluorescent Probes

et al. 2017

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Local environment of fluorescent dyes could strongly affects emission dynamics of the latter. In particular, both signal intensities and emission lifetimes are highly sensitive to solvent temperatures. Here, temperature-dependent behavior Rhodamine B fluorescence in water and ethanol solutions was experimentally investigated. Phase transition point between liquid water and ice was shown to have a dramatic impact on both in intensity (30-fold drop) and in lifetime (from 2.68 ns down to 0.13 ns) of the dye luminescence along with the shift of spectral maxima from 590 to 625 nm. At the same time, use of ethanol as solvent does not lead to any similar behavior. The reported results and approaches enable further investigations of dye-solvent interactions and studies of physical properties at phase transition points.

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Section: Introductionmentioning

confidence: 99%

Temperature and Phase Transition Sensing in Liquids with Fluorescent Probes

et al. 2017

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“…This wide availability has provided fertile ground for development of fluorescent nanosensors by a number of research groups around the world. Fluorescent sensors have been developed for physical properties such as temperature, [57][58][59][60] …”

Section: Polymeric Fluorescent Nanosensorsmentioning

confidence: 99%

Enhancing cell and gene therapy manufacture through the application of advanced fluorescent optical sensors (Review)

Harrison

Chauhan

2017

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Cell and gene therapies (CGTs) are examples of future therapeutics that can be used to cure or alleviate the symptoms of disease, by repairing damaged tissue or reprogramming defective genetic information. However, despite the recent advancements in clinical trial outcomes, the path to wide-scale adoption of CGTs remains challenging, such that the emergence of a “blockbuster” therapy has so far proved elusive. Manufacturing solutions for these therapies require the application of scalable and replicable cell manufacturing techniques, which differ markedly from the existing pharmaceutical incumbent. Attempts to adopt this pharmaceutical model for CGT manufacture have largely proved unsuccessful. The most significant challenges facing CGT manufacturing are process analytical testing and quality control. These procedures would greatly benefit from improved sensory technologies that allow direct measurement of critical quality attributes, such as pH, oxygen, lactate and glucose. In turn, this would make manufacturing more robust, replicable and standardized. In this review, the present-day state and prospects of CGT manufacturing are discussed. In particular, the authors highlight the role of fluorescent optical sensors, focusing on their strengths and weaknesses, for CGT manufacture. The review concludes by discussing how the integration of CGT manufacture and fluorescent optical sensors could augment future bioprocessing approaches.

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“…The luminescence ratiometric is needed for emission intensity change in the optical thermometry. Also, Ln 3+ ‐doped materials have appeared in the determination of optical thermometry . FIR provides an original temperature measurement method .…”

Section: Introductionmentioning

confidence: 99%

Tunable color emission in LaScO₃:Bi³⁺,Tb³⁺,Eu³⁺ phosphor

et al. 2020

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LaScO3:xBi3+,yTb3+,zEu3+ (x = 0 − 0.04, y = 0 − 0.05, z = 0 − 0.05) phosphors were prepared via high‐temperature solid‐state reaction. Phase identification and crystal structures of the LaScO3:xBi3+,yTb3+,zEu3+ phosphors were investigated by X‐ray diffraction (XRD). Crystal structure of phosphors was analyzed by Rietveld refinement and transmission electron microscopy (TEM). The luminescent performance of these trichromatic phosphors is investigated by diffuse reflection spectra and photoluminescence. The phenomenon of energy transfer from Bi3+ and Tb3+ to Eu3+ in LaScO3:xBi3+,yTb3+,zEu3+ phosphors was investigated. By changing the ratio of x, y, and z, trichromatic can be obtained in the LaScO3 host, including red, green, and blue emission with peak centered at 613, 544, and 428 nm, respectively. Therefore, two kinds of white light‐emitting phosphors were obtained, LaScO3:0.02Bi3+,0.05Tb3+,zEu3+ and LaScO3:0.02Bi3+,0.03Eu3+,yTb3+. The energy transfer was characterized by decay times of the LaScO3:xBi3+, yTb3+, zEu3+ phosphors. Moreover absolute internal QY and CIE chromatic coordinates are shown. The potential optical thermometry application of LaScO3:Bi3+,Eu3+ was based on the temperature sensitivity of the fluorescence intensity ratio (FIR). The maximum Sa and Sr are 0.118 K−1 (at 473.15 K) and 0.795% K−1 (at 448.15 K), respectively. Hence, the LaScO3:Bi3+,Eu3+ phosphor is a good material for optical temperature sensing.

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Thermo-optical characterization of fluorescent rhodamine B based temperature-sensitive nanosensors using a CMOS MEMS micro-hotplate

Cited by 54 publications

References 40 publications

Temperature and Phase Transition Sensing in Liquids with Fluorescent Probes

Temperature and Phase Transition Sensing in Liquids with Fluorescent Probes

Enhancing cell and gene therapy manufacture through the application of advanced fluorescent optical sensors (Review)

Tunable color emission in LaScO₃:Bi³⁺,Tb³⁺,Eu³⁺ phosphor

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Thermo-optical characterization of fluorescent rhodamine B based temperature-sensitive nanosensors using a CMOS MEMS micro-hotplate

Cited by 54 publications

References 40 publications

Temperature and Phase Transition Sensing in Liquids with Fluorescent Probes

Temperature and Phase Transition Sensing in Liquids with Fluorescent Probes

Enhancing cell and gene therapy manufacture through the application of advanced fluorescent optical sensors (Review)

Tunable color emission in LaScO3:Bi3+,Tb3+,Eu3+ phosphor

Contact Info

Product

Resources

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Tunable color emission in LaScO₃:Bi³⁺,Tb³⁺,Eu³⁺ phosphor