2023
DOI: 10.1021/acsapm.3c01699
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Thermo/Pressure-Sensitive Self-Fixation Surgical Meshes: The Role of Adhesive Hydrogels in Interface Attachment

Sonia Lanzalaco,
Xavier Sánchez,
Carlos Alemán
et al.

Abstract: Herein, an innovative self- and pressure-adhesive biomedical implant was developed. Tissue adhesion was achieved with a thermosensitive hydrogel based on poly­(N-isopropylacrylamide-co-acrylamide), PNIPAAm-co-PAAm, grafted on a substrate composed of knitted fibers of isotactic polypropylene mesh (PP), used as surgical mesh implants. The in vitro studies, carried out with porcine skin, showed an important role of the inclusion of acrylamide-based comonomer (AAm) in the thermosensitive hydrogel PNIPAAm matrix. T… Show more

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