Thermo‐Responsive Actuation of a DNA Origami Flexor

Turek, Vladimir A.; Chikkaraddy, Rohit; Cormier, Sean; Stockham, Bill; Ding, Tao; Keyser, Ulrich F.; Baumberg, Jeremy J.

doi:10.1002/adfm.201706410

Cited by 79 publications

(97 citation statements)

References 46 publications

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“…Thermoplasmonics is an emerging hot topic that offers a route to controllable actuation at the nanoscale and reversible plasmon tuning of sensing devices . The ability to manipulate nanoparticles in order to create and steer nanostructures is essential in many applications such as drug delivery, noninvasive microsurgery, nanoassembly, and fabrication …”

Section: Heating Up the Environmentmentioning

confidence: 99%

“…Recent key results have demonstrated that the actuation from the ANTs can be coordinated along a common direction, and that ANTs can power DNA origami constructs . Moreover, the polymer can be grown within the plasmonic hotspots, in a light‐guided and well‐controlled fashion .…”

Section: Introductionmentioning

confidence: 99%

“…Moreover, the polymer can be grown within the plasmonic hotspots, in a light‐guided and well‐controlled fashion . Additionally, some polymers are best attached to the plasmonic nanoparticles using for instance NH 2 groups (compared to SH, COOH, and H terminations); this is because the terminal group determines how close the nanoparticles are brought together in the contracted state . Additionally, ANTs can serve as miniature water pumps .…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

“Hot” in Plasmonics: Temperature‐Related Concepts and Applications of Metal Nanostructures

Kuppe

Rusimova

Ohnoutek

et al. 2019

Advanced Optical Materials

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Recent advances in nonlinear optics, hot electrons for renewable energy (e.g., solar cells and water‐splitting), acousto‐optics, nanometalworking, nanorobotics, steam generation, and photothermal cancer therapy are reviewed here. In all these areas, one of the key enabling properties is the ability of metallic nanoparticles to harvest and control light at the subwavelength scale by supporting coherent electronic oscillations, called localized surface plasmon resonances (LSPRs). Various physical properties and potential areas of application emerge depending on the decay mechanism of the LSPR and, especially, depending on the considered timescale. The field of plasmonics has mainly been associated with manipulating electromagnetic near‐fields at the nanoscale, where absorption is an obstacle. However, plasmonic absorption leads to a stream of temperature‐related phenomena that have only recently attracted significant attention. The goal of this review is to highlight exciting new areas of research (such as nanorobotics, nanometalworking, or acousto‐optical techniques) and to survey the most recent progress in more established areas (such as hot electrons, photothermal therapy, and plasmonic steam generation). To set each research area in context, the text is organized around the thermal cycle of the nanoparticles.

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Section: Heating Up the Environmentmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

“Hot” in Plasmonics: Temperature‐Related Concepts and Applications of Metal Nanostructures

Kuppe

Rusimova

Ohnoutek

et al. 2019

Advanced Optical Materials

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“…One approach toward the implementation of machine‐like behaviors in DNA origami structures is based on the creation of molecular assemblies, in which multiple origami subunits are connected with each other via simple machine elements such as pivots or hinges . When the subunits are further made to bind with each other through sufficiently weak interactions, which can be reversibly switched by external stimuli, the structural components can change their relative positions, resulting in an overall conformational change.…”

Section: Introductionmentioning

confidence: 99%

“…The stimuli and energy sources for the operation of such devices can be quite diverse, for instance, DNA strand displacement processes, binding of biomolecules through aptamers, environmental changes (e.g., changes in salt concentrations or physical stimuli such as temperature), or electric and magnetic fields . In many cases, “switchability” has been introduced by appropriate chemical modifications of the devices.…”

Section: Introductionmentioning

confidence: 99%

Periodic Operation of a Dynamic DNA Origami Structure Utilizing the Hydrophilic–Hydrophobic Phase‐Transition of Stimulus‐Sensitive Polypeptides

Goetzfried

Vogele

Mückl

et al. 2019

Small

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Dynamic DNA nanodevices are designed to perform structure‐encoded motion actuated by a variety of different physicochemical stimuli. In this context, hybrid devices utilizing other components than DNA have the potential to considerably expand the library of functionalities. Here, the reversible reconfiguration of a DNA origami structure using the stimulus sensitivity of elastin‐like polypeptides is reported. To this end, a rectangular sheet made using the DNA origami technique is functionalized with these peptides and by applying changes in salt concentration the hydrophilic–hydrophobic phase transition of these peptides actuate the folding of the structure. The on‐demand and reversible switching of the rectangle is driven by externally imposed temperature oscillations and appears at specific transition temperatures. Using transmission electron microscopy, it is shown that the structure exhibits distinct conformational states with different occupation probabilities, which are dependent on structure‐intrinsic parameters such as the local number and the arrangement of the peptides on the rectangle. It is also shown through ensemble fluorescence resonance energy transfer spectroscopy that the transition temperature and thus the thermodynamics of the rectangle‐peptide system depends on the stimuli salt concentration and temperature, as well as on the intrinsic parameters.

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