Recent researches of the novel 4D Einstein–Gauss–Bonnet (EGB) gravity have attracted great attention. In this paper, we investigate the validity of the weak cosmic censorship conjecture for a novel 4D charged EGB black hole with test charged scalar field and test charged particle respectively. For the test charged field scattering process, we find that both extremal and near-extremal black holes cannot be overcharged. For the test charged particle injection, to first order, an extremal black hole cannot be overcharged while a near-extremal 4D charged EGB black hole can be destroyed. To second order, however, both extremal and near-extremal 4D charged EGB black holes can be overcharged for positive Gauss–Bonnet coupling constant; for negative Gauss–Bonnet coupling constant, an extremal black hole cannot be overcharged and the validity of the weak cosmic censorship conjecture for a near-extremal black hole depends on the Gauss–Bonnet coupling constant.