Thermodynamic performance vs. dynamic stability in an enzymatic reaction model

Performance of a Simple Energetic-Converting Reaction Model Using Linear Irreversible Thermodynamics

“…which is remarkably similar to the linear approximation of Equation (10) reported by Diaz-Hernandez et al in Reference [15].…”

“…It is worthwhile to analyze Equation (15). From the scheme in Figure 1, we observe that it corresponds to three sequential equations, all three reactions can be lumped into a single global reaction with free energy change for this reaction as ∆G TOT = A(µ 1 − µ 4 ).…”

“…al. [15] for a similar model using a different approach. Furthermore, Figure 2 shows the efficiency plotted as a function of the stoichiometric coefficient for various values of q.…”

“…Moreover, it was reported [9][10][11] that thermal engines show some universality regarding the behavior of the efficiency when it works at the maximum power regime [11], although the analyzed models are different in nature and scale [12][13][14]. Recently, some thermal engines with kinetic [15][16][17] and mesoscopic [18] descriptions were published as examples of devices which convert non-thermal energy (mainly chemical energy) into useful work. The importance of these models is that the energy production processes seen in the molecular biological level obey similar principles as those observed in the classical thermal engines [19].…”

“…In this context, we have decided to study the thermodynamical properties of an energetic converting biological process, using for this purpose a simple model for an enzymatic reaction that couples one exothermic and one endothermic reaction in the same fashion described by Diaz-Hernandez et al [15], but now using the Linear Irreversible Thermodynamics (LIT) for three different operating regimes,;namely, Maximum Power Output (MPO), Maximum Ecological Function (MEF) and Maximum Efficient Power Function (MEPF), respectively.…”