Thermodynamic studies of thiamethoxam in nine pure solvents and one mixed solvent, solubility and correlation ranged from 278.15 to 323.15 K

Thermodynamic Modeling and Solubility Parameter of 2,6-Pyridinedicarboxylic Acid in Selected Solvents at Different Temperatures

“…Each solubility experiment was repeated at least three times with fresh initial materials to obtain reliable and reproducible results. The solubility value (in mol %) was reported as an average of three individual test results for each solvent at a given temperature using the equations below , where x 1 , m 1 , and M 1 are the mole fraction, mass, and molar weight of the solute in the solvent, respectively; m 2 and m 3 and M 2 and M 3 are the masses and molar weights of the solvents, respectively. The experimental solubility values for PDCA in pure solvents and in the binary mixtures are shown in Tables and , respectively.…”

“…For a better understanding and description of the solubility data, the solid–liquid equilibria were also expressed using activity coefficient obtained by applying Wilson, NRTL, and UNIQUAC models to the experimental data ,, where Δ fus H is the fusion enthalpy; T m is the melting temperature; R is the universal gas constant; and x 1 and γ 1 are the solute mole fraction and activity coefficient, respectively. All UNIQUAC volume and surface parameters, as listed in Table , were calculated using the Bondi group contribution method.…”

“…Wilson, NRTL, and UNIQUAC Models. For a better understanding and description of the solubility data, the solid− liquid equilibria were also expressed using activity coefficient obtained by applying Wilson, 23 NRTL, 24 and UNIQUAC 25 models to the experimental data 17,27,29 i k j j j y…”

“…i n d i v i d u a l n o t d i r e c t l y a s s o c i a t e d w i t h s c i t e i s p r o h i b i t e d .reproducible results. The solubility value (in mol %) was reported as an average of three individual test results for each solvent at a given temperature using the equations below28,29 …”

Diflufenican Dissolved in Different Aqueous Cosolvency Mixtures: Equilibrium Solubility Measurement and Thermodynamic Modeling

“…Therefore, scientific and accurate understanding of the dissolution information and thermodynamic properties of the drug is essential in the purification process. To improve the yield and purity of the diflufenican product avoiding the use of toxic, volatile, and environmental unfriendly solvents, some relatively green dissolves are selected. − Due to the defect of poor water solubility, important drugs often fail to fully exert their effects. Further, the development of some pharmaceutical dosage forms and the exploration of drug mechanisms are also limited due to their poor water solubility.…”