Thermodynamic Study of the Inclusion Interaction between Gemini Surfactants and Cyclodextrins by Isothermal Titration Microcalorimetry

Self-assembly of sodium bis(2-ethylhexyl) sulfosuccinate in aqueous solutions: Modulation of micelle structure and interactions by cyclodextrins investigated by small-angle neutron scattering

“…HP-β-CD forms mainly 1:1 complexes with SDS while α-CD forms both 1:1 and 2:1 complexes with SDS, thus HP-β-CD can bind with a higher amount of SDS compared to α-CD. Since α-CD can apparently form only 1:1 complexes [34] with AOT, while it can form both 1:1 and 2:1 complexes with SDS, the effectiveness of α-CD in modulating AOT micelles is higher compared to the SDS micelles. For example, at C α-CD = C Surfactant , the slope of decrease in the aggregation number per unit increase in the α-CD concentration is 3.5% for AOT micelles, higher (double) than that observed for SDS micelles,~1.8%.…”

“…Specifically, the inclusion complexation of AOT with α-cyclodextrin (6 member glucose ring), β-cyclodextrin (7 member glucose ring) and γ-cyclodextrin (8 member glucose ring) was examined using isothermal titration calorimetry [34] to suggest that AOT forms primarily 1:1 CD:AOT complexes with α-, β-or γ-CD. The binding constant values of 170, 180, 490 M −1 for 1:1 CD:AOT inclusion complexes of α-CD, β-CD, and γ-CD, respectively [34], are lower compared to binding constants for 1:1 CD:surfactant complexation with the single-tail anionic surfactant sodium dodecyl sulfate (SDS) (21,000 M −1 for 1:1 α-CD:SDS or β-CD:SDS complexation) [30], which can be attributed to lower hydrophobic interactions between the two hydrophobic, branched tails of AOT and the CD cavity compared to the single-tail interactions of SDS with the CD cavity [34]. Similar observations on the binding constants of β-cyclodextrin with AOT and other surfactants using conductivity measurements have been reported by Palepu et al [35].…”

“…To the best of our knowledge, there are only two published studies on the complexation of cyclodextrins with AOT in aqueous solutions at AOT concentrations below the CMC [34,35]. The effects of CD-AOT binding in water at AOT concentration higher than CMC have not been explored yet.…”

Characterization of the host–guest complex of a curcumin analog with β-cyclodextrin and β-cyclodextrin–gemini surfactant and evaluation of its anticancer activity

“…This finding is consistent with other studies that show that the CD cavity has the affinity to accommodate the tail of the gemini surfactants and other double-chain surfactants. [34][35][36][37][38][39] Moreover, the thermal degradation of NC 2067 complexes formed with CD or CDgemini surfactant started at higher temperatures in comparison to that of free NC 2067, suggesting the formation of a more stable complex. Similar thermal behavior was observed in the case of complexation of sulfamethoxazole with hydroxypropyl-CD, wherein the degradation temperature of the pure compound shifted from 200°C to 243°C in the complex, confirming that the inclusion complex is more stable than the drug.…”

Tenzidek zárványkomplex képződésének vizsgálata folyadékfázisban és adszorpciójuk tanulmányozása szilárd/folyadék határfelületen

“…Az irodalmat tanulmányozva, kiderül számos publikáció áll rendelkezésre gemini tenzidek és ciklodextrinek közötti zárványkomplex képződés vizsgálatára vonatkozóan [158][159][160][161][162][163].…”