Theta burst stimulation of dorsolateral prefrontal cortex modulates pathological language switching: A case report

Nardone, Raffaele; Blasi, Pierpaolo De; Bergmann, Jürgen; Caleri, Francesca; Tezzon, Frediano; Ladurner, G.; Golaszewski, Stefan; Trinka, Eugen

doi:10.1016/j.neulet.2010.10.060

Cited by 19 publications

(8 citation statements)

References 25 publications

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“…Nardone et al (2011) have recently reported that excitatory TMS of the left DLPFC transiently alleviated pathological language switching in a bilingual patient who had suffered a left frontal stroke.…”

Section: Intracranial Electrical Stimulation and Transcranial Magnetimentioning

confidence: 99%

Executive Control of Language in the Bilingual Brain: Integrating the Evidence from Neuroimaging to Neuropsychology

Hervais-Adelman¹,

Moser-Mercer²,

Golestani³

2011

Front. Psychology

147

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In this review we will focus on delineating the neural substrates of the executive control of language in the bilingual brain, based on the existing neuroimaging, intracranial, transcranial magnetic stimulation, and neuropsychological evidence. We will also offer insights from ongoing brain-imaging studies into the development of expertise in multilingual language control. We will concentrate specifically on evidence regarding how the brain selects and controls languages for comprehension and production. This question has been addressed in a number of ways and using various tasks, including language switching during production or perception, translation, and interpretation. We will attempt to synthesize existing evidence in order to bring to light the neural substrates that are crucial to executive control of language.

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Section: Intracranial Electrical Stimulation and Transcranial Magnetimentioning

confidence: 99%

Executive Control of Language in the Bilingual Brain: Integrating the Evidence from Neuroimaging to Neuropsychology

Hervais-Adelman¹,

Moser-Mercer²,

Golestani³

2011

Front. Psychology

147

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“…Importantly, the high (and sometimes optimal) results observed in our study were obtained through highly sensitive instruments. The BAT (Paradis, 1987) is the most widely used battery to test bilinguals after stroke and other neurological disorders (Fabbro, 2001; Zanini et al, 2004; Lorenzen and Murray, 2008; Tavano et al, 2008; Faroqi-Shah et al, 2010; Gomez-Ruiz and Aguilar-Alonso, 2011; Nardone et al, 2011; Paradis and Libben, 2014; Paplikar et al, 2018). In addition, it has been rigorously adapted for more than 70 languages (Paradis and Libben, 2014) and has proved to be sensitive to deficits associated with RH damage in patients with different language pair structures and showing different recovery damage (Fabbro and Paradis, 1995; Aglioti et al, 1996; Fabbro et al, 2000; Fabbro, 2001; Abutalebi et al, 2009).…”

Section: Discussionmentioning

confidence: 99%

Rethinking the Neural Basis of Prosody and Non-literal Language: Spared Pragmatics and Cognitive Compensation in a Bilingual With Extensive Right-Hemisphere Damage

et al. 2019

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Above and beyond the critical contributions of left perisylvian regions to language, the neural networks supporting pragmatic aspects of verbal communication in native and non-native languages (L1s and L2, respectively) have often been ascribed to the right hemisphere (RH). However, several reports have shown that left-hemisphere activity associated with pragmatic domains (e.g., prosody, indirect speech, figurative language) is comparable to or even greater than that observed in the RH, challenging the proposed putative role of the latter for relevant domains. Against this background, we report on an adult bilingual patient showing preservation of pragmatic verbal skills in both languages (L1: Spanish, L2: English) despite bilateral damage mainly focused on the RH. After two strokes, the patient sustained lesions in several regions previously implicated in pragmatic functions (vast portions of the right fronto-insulo-temporal cortices, the bilateral amygdalae and insular cortices, and the left putamen). Yet, comparison of linguistic and pragmatic skills with matched controls revealed spared performance on multiple relevant tasks in both her L1 and L2. Despite mild difficulties in some aspects of L2 prosody, she showed no deficits in comprehending metaphors and idioms, or understanding indirect speech acts in either language. Basic verbal skills were also preserved in both languages, including verbal auditory discrimination, repetition of words and pseudo-words, cognate processing, grammaticality judgments, equivalent recognition, and word and sentence translation. Taken together, the evidence shows that multiple functions of verbal communication can be widely spared despite extensive damage to the RH, and that claims for a putative relation between pragmatics and the RH may have been overemphasized in the monolingual and bilingual literature. We further discuss the case in light of previous reports of pragmatic and linguistic deficits following brain lesions and address its relation to cognitive compensation in bilingual patients.

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“…Although this area is not traditionally included in the frontotemporal network involved in linguistic processing [ 19 , 20 , 22 ], some studies have suggested otherwise (e.g., [ 27 ]). Nevertheless, a careful examination of the literature suggests that DLPFC might be involved in linguistic (and nonlinguistic) tasks requiring behavioural control and inhibition, such as language switch in bilingual individuals [ 27 , 50 ], which were not employed in our study. Also, its role might be correlational in the processing of linguistic information, but not causally related to the direct acquisition of new vocabulary.…”

Section: Discussionmentioning

confidence: 99%

“…Aside from the “classical” language areas of Broca and Wernicke [ 19 , 20 ], linguistic processing and production are also associated with other areas of the temporal lobe (e.g., lateral and anterior temporal cortex), auditory cortex, and basal ganglia [ 21 – 26 ]. Yet, it is still debated whether this “linguistic network” is actually larger and encompasses neighbouring areas, such as the posterior parietal cortex [ 24 ] and the dorsolateral prefrontal cortex (DLPFC [ 27 ]). The posterior parietal cortex possesses extensive connections with posterior language areas (e.g., Wernicke's area [ 28 ]) and is likely to be involved in linguistic processing [ 24 ].…”

Section: Introductionmentioning

confidence: 99%

“…The long-term effect of brain stimulation on foreign vocabulary acquisition was assessed in a testing session held seven days after the main session, and here participants did not receive any stimulation. Based on the findings of previous studies using different techniques (e.g., [ 24 , 27 ]), we expected to find that, compared to sham stimulation, tRNS on the frontal or the parietal areas would reveal which areas produce long-term benefit (e.g., [ 16 ]) in foreign vocabulary acquisition.…”

Section: Introductionmentioning

confidence: 99%

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Neural Stimulation Has a Long-Term Effect on Foreign Vocabulary Acquisition

2015

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Acquisition of a foreign language is a challenging task that is becoming increasingly more important in the world nowadays. There is evidence suggesting that the frontal and temporal cortices are involved in language processing and comprehension, but it is still unknown whether foreign language acquisition recruits additional cortical areas in a causal manner. For the first time, we used transcranial random noise stimulation on the frontal and parietal brain areas, in order to compare its effect on the acquisition of unknown foreign words and a sham, or placebo, condition was also included. This type of noninvasive neural stimulation enhances cortical activity by boosting the spontaneous activity of neurons. Foreign vocabulary acquisition was tested both immediately and seven days after the stimulation. We found that stimulation on the posterior parietal, but not the dorsolateral prefrontal cortex or sham stimulation, significantly improved the memory performance in the long term. These results suggest that the posterior parietal cortex is directly involved in acquisition of foreign vocabulary, thus extending the “linguistic network” to this area.

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Theta burst stimulation of dorsolateral prefrontal cortex modulates pathological language switching: A case report

Cited by 19 publications

References 25 publications

Executive Control of Language in the Bilingual Brain: Integrating the Evidence from Neuroimaging to Neuropsychology

Executive Control of Language in the Bilingual Brain: Integrating the Evidence from Neuroimaging to Neuropsychology

Rethinking the Neural Basis of Prosody and Non-literal Language: Spared Pragmatics and Cognitive Compensation in a Bilingual With Extensive Right-Hemisphere Damage

Neural Stimulation Has a Long-Term Effect on Foreign Vocabulary Acquisition

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