Thiamine Absorption in Old Age

Thomson, Allan D.

doi:10.1159/000244973

Cited by 13 publications

(2 citation statements)

References 9 publications

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“…Evidence of thiamine deficiency, as determined by measurement of thiamine‐dependent transketolase activity, has been found in 23–79 percent of elderly subjects; thiamine supplementation restored normal levels (39, 40). Thiamine malabsorption has not been implicated as a cause of thiamine deficits in the elderly (41); increasing age is believed to be the factor responsible for lowered thiamine (42).…”

Section: Discussionmentioning

confidence: 99%

Vitamin Profiles in Elderly Persons Living at Home or in Nursing Homes, versus Profile in Healthy Young Subjects

Baker¹,

Frank²,

Thind³

et al. 1979

J American Geriatrics Society

124

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The vitamin profile of 473 elderly persons was compared with that of 204 healthy volunteers (controls). Of the 473 elderly, 327 (mean age 87) lived in nursing homes, and 146 (mean age 77) lived at home. The 204 controls were in the 20–50 year age group. The circulating levels of biotin, pantothenate, riboflavin, vitamins A, B6, B12, C, E, folate, thiamine, nicotinate, and carotenes were determined in all groups. Hypovitaminemia was not obvious for biotin, pantothenate, riboflavin, vitamins A, E, and carotenes in either the institutional or non‐institutional elderly. Thiamine, vitamin C and vitamin B12 levels were strikingly depressed in the non‐institutional elderly as compared with the institutional population or the controls. Over 30 percent of the institutional elderly had vitamin B6 and nicotinate hypovitaminemia compared to the controls. Both the institutional and the non‐institutional elderly showed depressed levels of folate and vitamin B12. Vitamin supplementation reduced the percentage of folate and B12 deficits. The marked vitamin deficits in the institutional population, in descending order of incidence were: vitamin B6, nicotinate, vitamin B12, folate, thiamine, and ascorbate, whereas the pattern for the non‐institutional elderly was: vitamin B12, thiamine, ascorbate, vitamin B6, nicotinate, and folate. In the 473 elderly studied, vitamin B6, nicotinate, and vitamin B12, in that order, were the most common deficits; folate, thiamine and ascorbate deficits comprised a lesser percentage. The role of vitamin deficits and the effects upon the aging population are discussed.

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Section: Discussionmentioning

confidence: 99%

Vitamin Profiles in Elderly Persons Living at Home or in Nursing Homes, versus Profile in Healthy Young Subjects

Baker¹,

Frank²,

Thind³

et al. 1979

J American Geriatrics Society

124

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show abstract

“…In one such study of free-living elderly, 11% showed thiamine hypovitaminemia (11). There is no agreement on whether thiamine absorption in man changes with age (84, 151). A variant of this assay is the transketolase-activated coefficient, in which the response of the enzyme to thiamine pyrophosphate is measured.…”

Section: Vitamin B]mentioning

confidence: 99%

Nutritional Requirements of the Elderly

Munro¹,

Suter²,

Russell³

1987

Annu. Rev. Nutr.

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The Gastrointestinal Tract

Holt

1995

Comprehensive Physiology

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The sections in this article are: Salivary Glands Stomach Gastric Secretion Small Intestine Morphology Brush Border Membranes Enzymes Intestinal Permeability Protein Synthesis Intestinal Absorption Gut‐Associated Immune System Splanchnic Blood Flow Gastrointestinal Motility Esophagus Stomach Neuromuscular Functioning Colon and Rectum Pancreas Liver and Biliary Tree Morphology Age‐Associated Effects Consequences of Aging Bile Gastrointestinal Hormones Cellular Proliferation Esophagus and Stomach Small Intestine Colon Effects of Caloric Restriction

show abstract

Thiamine Absorption in Old Age

Cited by 13 publications

References 9 publications

Vitamin Profiles in Elderly Persons Living at Home or in Nursing Homes, versus Profile in Healthy Young Subjects

Vitamin Profiles in Elderly Persons Living at Home or in Nursing Homes, versus Profile in Healthy Young Subjects

Nutritional Requirements of the Elderly

The Gastrointestinal Tract

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