“…The more controversial aspect related to the structure of the sacculus is the orientation and distribution of the glycan strands (Formanek et al, 1976;Verwer et al, 1978;Höltje, 1998;Koch, 1998aKoch, , b, 2000aDmitriev et al, 1999Dmitriev et al, , 2003Yao et al, 1999;Pink et al, 2000;Vollmer & Höltje, 2004;Meroueh et al, 2006). Most available evidence favoured models postulating glycan strands oriented parallel to the cell surface, and in most cases with the glycan backbones transversal to the cell longitudinal axis.…”