Thickness of Malignant Melanoma: Global Analysis of Related Factors

Kopf, Alfred W.; Welkovich, Bruce; Frankel, Renee E.; Stoppelmann, Edward J.; Bart, Robert S.; Rogers, Gary S.; Rigel, Darrell S.; Friedman, Robert J.; Levenstein, Marcia; Gumport, Stephen L.; Hennessey, Patrick

doi:10.1111/j.1524-4725.1987.tb03726.x

Cited by 96 publications

(44 citation statements)

References 358 publications

(506 reference statements)

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“…27 The importance of lesion evolution as a cardinal feature of cutaneous melanoma is also well supported. 28 The need to recognize lesion change in our acronym was met by our enhancement of the ABCDs through the addition of "E" for "Evolving." 11,29 This augmentation substantially enhanced the ability of physicians and laypersons to recognize melanomas at earlier stages.…”

Section: Basic Factors In Early Diagnosismentioning

confidence: 99%

The Evolution of Melanoma Diagnosis: 25 Years Beyond the ABCDs

Rigel

Russak

Friedman

2010

CA: A Cancer Journal for Clinicians

343

274

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Early detection of malignant melanoma remains the key factor in lowering mortality from this cancer. Recognizing the importance of this issue 25 years ago, our group at New York University published in CA: A Cancer Journal for Clinicians the mnemonic "ABCD" to facilitate the early diagnosis of melanoma. Studies have demonstrated the usefulness of this paradigm in enhancing early melanoma diagnosis as a part of clinical examinations, mass screenings, and public education programs. Approaches to melanoma diagnosis have dynamically evolved during the ensuing quarter century. In the 1990s, dermoscopy enabled the recognition of new subsurface features to differentiate between malignant and benign pigmented lesions. During the last decade, new computer-based technologies have improved diagnostic sensitivity and specificity and may result in optimizing lesion selection for biopsy and pathology review. Despite all of the advances in melanoma diagnosis, timely recognition, detection, and rapid treatment of melanoma remain critical. Although pathologic examination remains the gold standard for diagnosis, this cancer has the potential to be diagnosed through noninvasive approaches because of its cutaneous location. From the development of the ABCDs through current attempts that use complex computer algorithms and genetic markers, a clinician's ability to detect melanoma in its earliest form has been augmented. However, a "good clinical eye" is still fundamental to selecting the lesions for evaluation among the sea of those that are prevalent. As current approaches are refined and new techniques are developed, the improved ability to diagnose this cancer will hopefully enhance reaching the goal of reducing melanoma mortality. CA Cancer J Clin 2010;60:301-316.

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Section: Basic Factors In Early Diagnosismentioning

confidence: 99%

The Evolution of Melanoma Diagnosis: 25 Years Beyond the ABCDs

Rigel

Russak

Friedman

2010

CA: A Cancer Journal for Clinicians

343

274

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“…Earlier analyses in the United States have found that older men have thicker tumors 1 and higher mortality rates than women. 2,10 Data from Australia and Europe have suggested that thick lesions are more often nodular [4][5][6]11,12 and predominantly observed in older men. [4][5][6][11][12][13] However, US population-based databases have not previously been examined for the interrelationships of tumor thickness, histologic subtype, sex, and age.…”

Section: Commentmentioning

confidence: 99%

Early Detection of Thick Melanomas in the United States

Demierre¹,

Chung²,

Miller³

et al. 2005

Arch Dermatol

129

102

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“…[17][18][19][20][21] Education in SSE and skills training that builds on the commonly recognized changes in a mole may improve the ability of laypersons to detect evolving lesions. Change in size and/or color and very dark colors are the features most commonly reported by patients.…”

Section: Commentmentioning

confidence: 99%

Skills Training to Learn Discrimination of ABCDE Criteria by Those at Risk of Developing Melanoma

Robinson¹,

Turrisi²

2006

Arch Dermatol

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To develop skin self-examination skills by improving the use of the ABCDE criteria by those at risk of developing melanoma.Design: Ten single-sex groups of 10 unrelated adults received a knowledge-based intervention followed by skills training.Setting: Classroom in the ambulatory care area of a hospital.Patients: One hundred unrelated adults with either a personal or family history of melanoma and no previous skin self-examination counseling.Interventions: A dermatologist presented information, and each subject read a brochure and reviewed a bookmark. The facilitator led the group discussions about scoring each feature and the decision to seek medical care. Measurement of moles with a ruler and a pencil eraser and the use of an illuminated magnifying lens were demonstrated. Preintervention and postintervention assessments were performed for each intervention.

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Thickness of Malignant Melanoma: Global Analysis of Related Factors

Cited by 96 publications

References 358 publications

The Evolution of Melanoma Diagnosis: 25 Years Beyond the ABCDs

The Evolution of Melanoma Diagnosis: 25 Years Beyond the ABCDs

Early Detection of Thick Melanomas in the United States

Skills Training to Learn Discrimination of ABCDE Criteria by Those at Risk of Developing Melanoma

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