2005
DOI: 10.1007/s11172-005-0333-1
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Thienopyridines: synthesis, properties, and biological activity

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Cited by 99 publications
(85 citation statements)
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“…On treatment of compound 7a with phenacyl bromide in boiling ethanol containing an equimolar amount of sodium acetate, the product was identified as 2H-pyrido[3'',2'':4',5']thieno [3',2':4,5]pyrimido [1,6-b] [1,2,4]triazine 12 rather than the related isomer 13 (Scheme 3). This assignment based on the spectral data of this product.…”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…On treatment of compound 7a with phenacyl bromide in boiling ethanol containing an equimolar amount of sodium acetate, the product was identified as 2H-pyrido[3'',2'':4',5']thieno [3',2':4,5]pyrimido [1,6-b] [1,2,4]triazine 12 rather than the related isomer 13 (Scheme 3). This assignment based on the spectral data of this product.…”
Section: Resultsmentioning
confidence: 99%
“…1,2 Some of them proved to possess antiviral, 3,4 anti-diabetic, 5 antimicrobial, 6,7 anti-inflammatory, 8 antitumor, 9 antiparasitic 10 and neurotropic activities. 11 Also, thienopyrimidine derivatives have been the subject of several chemical and biological studies on account of their wide spectrum of biological activity.…”
Section: Introductionmentioning
confidence: 99%
“…Thorpe-Ziegler 环化反应 [20] 是制备杂环化合物非常 重要的反应之一. 本工作设计以易得的 7-氯甲基噻唑并 [3,2-a]嘧啶-5-酮(1) [21] 为基础原料, 于 N,N-二甲基甲酰 [22] , 在我们的研究中发现 [19] , 该催化剂对噻唑并嘧啶类 稠杂环化合物的合成过程中同样起到良好的催化作用.…”
Section: 中间体 3 的合成unclassified
“…This is associated primarily with the great practical importance of many derivatives of thieno [2,3-b]pyridine (Litvinov et al, 2005). The spectrum of biological activities of this class of compounds is rather broad and includes antiviral (Attaby et al, 2007), antidiabetic (Bahekar et al 2007) and antimicrobial (Abdel-Rahman et al, 2003).…”
Section: Structure Descriptionmentioning
confidence: 99%