Thifluzamide, Fludioxonil, and Clothianidin as Seed Treatment Can Efficiently Control Major Soil-Borne Diseases, Aphids (Aphidoidea spp.), and Residue Distribution in the Field

Abstract

Combined seed treatment with neonicotinoids and fungicides offers a potential control measure for pest management at the wheat seeding stage. In this study, a novel, highly-efficient seed-coating agent was prepared using thifluzamide, fludioxonil, and clothianidin as its active components and other additives (abbreviated to TFC). Laboratory experiments and field trials revealed a positive effect on germination, plant height, and root length, with 90% control efficiency on wheat sharp eyespots and aphid infestations. Meanwhile, the distribution of thifluzamide, fludioxonil, and clothianidin residues in the wheat plants at harvest was below 0.05 mg/kg both at the recommended dosage and at 2.0 times the recommended dose. Furthermore, an artificial soil assay of biotoxicity in earthworms revealed a low level of toxicity at LC50 > 10 mg/kg. Overall, these findings suggest that TFC has the potential to control major soil-borne diseases and pest infestations in wheat, offering an environmentally-friendly alternative to more toxic pesticides.

Preparation of Thifluzamide Polylactic Acid Glycolic Acid Copolymer Microspheres and Its Effect on the Growth of Cucumber Seedlings

“…Thifluzamide is also very effective against a wide range of fungal diseases and has special effects on sheath blight. It is reported that thifluzamide, as a seed treatment, can efficiently control major soil-borne diseases in the field [ 26 ]. It has obvious fungal inhibition on wheat sharp eyespot, take-all, and root rot of wheat through fungal inhibition tests [ 27 ].…”